Despite several advancements in care over the last few decades, sepsis continues to carry a
high morbidity and mortality burden in the United States. With its varied presentations, cases …

Standardization of definitions has been considered important in sepsis to facilitate accurate
diagnosis and treatment, to clarify patient inclusion criteria for clinical trials, and to enable …

This book is designed to provide a comprehensive and state-of-the-art resource for
clinicians who care for patients with sepsis and research scientist alike,. Patients with severe …

Sepsis is a common condition with high morbidity and mortality. Although many patients may
require critical care, this article considers the features of sepsis that are of most relevance to …

In 1991, experts from diverse specialties developed the first consensus definition of sepsis
(1). Sepsis was characterized as a systemic inflammatory response syndrome (SIRS) to …

Sepsis as a disease has received renewed interests since recent publications of a revised
clinical definition and crucial clinical trials showing the benefits of early goal-directed …

Sepsis remains a serious cause of morbidity and mortality, and the pathophysiology of the
disease is not clear. The definition of the clinical manifestations of sepsis is ever evolving …

Sepsis is one of the most common deadly diseases. Despite its remarkable incidence, and
despite the progress which has been made in understanding this complex syndrome, for …

Sepsis is a life-threatening syndrome of a dysregulated host response to infection. Despite
advances in diagnosis and treatment, sepsis remains a significant cause of morbidity and …

Importance Definitions of sepsis and septic shock were last revised in 2001. Considerable
advances have since been made into the pathobiology (changes in organ function …