The frequency of complications in a cohort of patients diagnosed with hemophilia A and hemophilia B receiving prophylactic treatment in Colombia: A retrospective …

JE Machado Alba, JD Wilches-Gutierrez… - PLoS …, 2023 - journals.plos.org
Introduction Hemophilia A and B are disorders associated with the deficit of coagulation
factors VIII and IX. Objective Was to determine the incidence of complications in a cohort of …

A multicentre real-world data study to assess the bleeding rate and management of patients with haemophilia A and factor VIII inhibitors in Argentina

D Neme, IR Mejía, L Elelhou… - Blood Coagulation & …, 2021 - journals.lww.com
The development of inhibitors against factor VIII (FVIII) concentrates is a severe complication
of treatment for patients with haemophilia. We investigated annualized bleeding rates …

Factors Involved in the Development of Inhibitory Antibodies in Patients with Hemophilia in Colombia: A Case-Control Study

JE Machado-Alba, LA Chica-Quintero… - Clinical Medicine …, 2020 - journals.sagepub.com
Background: The appearance of inhibitory antibodies against antihemophilic factors is one
of the most serious complications related to hemophilia. Objective: The objective of this …

[PDF][PDF] Economic impact of hemophilia type A and B in Mexico

F Carlos-Rivera, R Gasca-Pineda, A Majluf-Cruz… - Gac Med Mex, 2016 - anmm.org.mx
Background: The treatment of hemophilia generates a disproportionally large economic
impact relative to its prevalence. Objective: To determine the economic impact of hemophilia …

[HTML][HTML] Epidemiology, patient journey and unmet needs related to hemophilia in Brazil: a scoping review with evidence map

NB Schneider, CLP de Araujo, HWG Dos Santos… - … , Transfusion and Cell …, 2024 - Elsevier
Introduction Brazil is one of the countries with the largest population of people with
hemophilia (PwH) worldwide. In this scoping review, we aim to investigate the Brazilian …

[HTML][HTML] Clinical outcome and incidence of inhibitor development in severe hemophilia patients receiving low-dose prophylaxis: a 3-year follow-up study in Senegal …

SA Touré, M Seck, D Sy, AB Senghor… - … , Transfusion and Cell …, 2023 - SciELO Brasil
ABSTRACT Introduction: In Africa, where access to diagnosis and treatment of hemophilia is
the lowest in the world, prophylaxis is rarely used in preference to on-demand treatment …

Haemophilia A: A Review of Clinical Manifestations, Treatment, Mutations, and the Development of Inhibitors

S Sarmiento Doncel, GA Díaz Mosquera, JM Cortes… - Hematology …, 2023 - mdpi.com
The purpose of this narrative review was to provide an overview that allows readers to
improve their understanding of hemophilia A, which is considered a genetic disease with a …

Hemophilia A in Brazil–epidemiology and treatment developments

AA Ferreira, ICG Leite… - Journal of blood …, 2014 - Taylor & Francis
Hemophilia A is an inherited disorder characterized by deficiency of coagulation factor VIII,
which predisposes patients to bleeding events. Treatment is based on replacement of the …

Prophylaxis therapy in haemophilia A: current situation in Spain

JF Lucía, JA Aznar, L ABAD‐FRANCH… - …, 2011 - Wiley Online Library
The Spanish Epidemiological Study in Haemophilia carried out in 2006 enrolled 2400
patients [2081–86.7% with haemophilia A (HA) and 319–13.3% with haemophilia B]; 465 of …

Limitations of prophylactic treatment in patients with hemophilia

MFL Fernández - Blood Coagulation & Fibrinolysis, 2019 - journals.lww.com
Prophylaxis with factor VIII concentrates is the cornerstone of treatment for severe
hemophilia A. In children, early onset of primary and secondary prophylaxis is the gold …