A cancer cell-centric view has long dominated the field of cancer biology. Research efforts
have focussed on aberrant cancer cell signalling pathways and on changes to cancer cell …

Cancer stem cells are believed to be a subset of heterogeneous tumour cells responsible for
tumour initiation, growth, local invasion, and metastasis. In breast cancer, numerous factors …

The innate immune system ensures effective protection against foreign pathogens and plays
important roles in tissue remodeling. There are many types of innate immune cells, including …

Breast cancer affects millions of women worldwide, leading to many deaths and significant
economic burden. Although there are numerous treatment options available, the huge …

The role of the immune system in shaping cancer development and patient prognosis has
recently become an area of intense focus in industry and academia. Harnessing the …

Inflammation is now recognized as a hallmark of cancer. Genetic changes in the cancer cell
are accepted as the match that lights the fire, whilst inflammation is seen as the fuel that …

A cancer cell-centric view has long dominated the field of cancer biology. Research efforts
have focussed on aberrant cancer cell signalling pathways and on changes to cancer cell …

Immunology and Breast Cancer: Toward a New Way of Understanding Breast Cancer and
Developing Novel Therapeutic Strategies Page 1 372 Clinical Advances in Hematology & …

Myeloid-derived suppressor cells (MDSCs) play a pivotal role in promoting tumor growth
and metastasis and can even decrease the efficacy of immunotherapy. In breast cancer …

Myeloid-derived suppressor cells (MDSCs) are a population of immature myeloid cells
defined by their suppressive actions on immune cells such as T cells, dendritic cells, and …