A family of gold (I)-phosphonium-phosphine complexes was synthesized thanks to an
efficient 5-step strategy, which involves a phospha-Fries rearrangement. It enables the facile …

Cancer is one of the leading causes of morbidity and mortality worldwide. Colorectal cancer
(CRC) is the third most frequently diagnosed cancer in men and the second in women …

In recent years, a few successful attempts were made to repurpose the clinically approved
antiarthritic gold drug, Auranofin (AF), as an anticancer agent. The present study shows that …

Gold-based compounds are of great interest in the field of medicinal chemistry as novel
therapeutic (anticancer) agents due to their peculiar reactivity and mechanisms of action …

Gold-based anticancer agents have gained the widespread attention of medicinal inorganic
chemists due to their unique chemical properties and strong antiproliferative potency …

Gold complexes have been traditionally employed in medicine, and currently, some gold (I)
complexes, such as auranofin, are clinically used in the treatment of rheumatoid arthritis. In …

The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …

Six structurally diverse cytotoxic gold compounds are reported to cause profound and
differential inhibition of the three main catalytic activities of purified 20S proteasome whilst …

Gold (III) complexes have been studied for the past years due to their anticancer properties
and great affinity to biotargets, such as enzymes and proteins, which support their …

The antiproliferative activity of the gold complex [Au (tpp) Cl](1)(tpp= triphenyphosphine)
against human breast adenocarcinoma cells (MCF-7) and normal human fetal lung …