Synthesis, properties, and antitumor effects of a new mixed phosphine gold (I) compound in human colon cancer cells

G Lupidi, L Avenali, M Bramucci, L Quassinti… - Journal of Inorganic …, 2013 - Elsevier
The antineoplastic potential of a new stable mixed phosphine gold (I) complex containing
tris (tert-butyl) phosphine (tBu3P) and bis (diphenylphosphino) ethene (dppet), namely [Au …

Mechanistic studies on two dinuclear organogold(iii) compounds showing appreciable antiproliferative properties and a high redox stability

C Gabbiani, A Casini, G Kelter, F Cocco… - Metallomics, 2011 - academic.oup.com
Two dinuclear oxo-bridged organogold (iii) compounds, namely [(N, N, C) 2Au2 (μ-O)][PF6]
2 (with N, N, CH= 6-(1-methylbenzyl)-2, 2′-bipyridine, Au22O1; or 6-(1, 1-dimethylbenzyl) …

Anti-cancer potential of gold complexes

ERT Tiekink - Inflammopharmacology, 2008 - Springer
A full range of gold compounds is currently being investigated for their potential as anti-
tumor agents. Gold (I) compounds related to the anti-arthritic drug\rm Auranofin^\circledR …

Gold organometallics with biological properties

MA Cinellu, I Ott, A Casini - Bioorganometallic Chemistry, 2014 - Wiley Online Library
This chapter compiles advances in the investigation of the biological properties of gold
organometallic compounds with possible therapeutic applications, in particular as …

In vivo anticancer activity, toxicology and histopathological studies of the thiolate gold (I) complex [Au (Spyrimidine)(PTA-CH2Ph)] Br

E García-Moreno, S Gascón… - Anti-Cancer Agents …, 2015 - ingentaconnect.com
A physiologically stable thiolate gold (I) derivative [Au (Spyrimidine)(PTA-CH2Ph)] Br has
shown inhibition in colon cancer proliferation of Caco-2/TC7, Caco-2/PD7 and HTC-116 …

Gold (I/III)-phosphine complexes as potent antiproliferative agents

JH Kim, E Reeder, S Parkin, SG Awuah - Scientific reports, 2019 - nature.com
The reaction of gold reagents [HAuCl4• 3H2O],[AuCl (tht)], or cyclometalated gold (III)
precursor,[C^ NAuCl2] with chiral ((R, R)-(-)-2, 3-bis (t-butylmethylphosphino) quinoxaline) …

Mass spectrometry uncovers molecular reactivities of coordination and organometallic gold (III) drug candidates in competitive experiments that correlate with their …

SM Meier, C Gerner, BK Keppler, MA Cinellu… - Inorganic …, 2016 - ACS Publications
The reactivity of three cytotoxic organometallic gold (III) complexes with cyclometalated C, N,
N and C, N ligands (either six-or five-membered metallacycles), as well as that of two …

Gold (III) complexes as potential antitumor agents: solution chemistry and cytotoxic properties of some selected gold (III) compounds

L Messori, F Abbate, G Marcon, P Orioli… - Journal of medicinal …, 2000 - ACS Publications
Gold (III) complexes generally exhibit interesting cytotoxic and antitumor properties, but until
now, their development has been heavily hampered by their poor stability under …

A soluble bis-chelated gold (I) diphosphine compound with strong anticancer activity and low toxicity

Y Wang, M Liu, R Cao, W Zhang, M Yin… - Journal of Medicinal …, 2013 - ACS Publications
Gold-containing compounds have shown anticancer potential, but their clinical applications
have been severely limited by poor stability and high toxicity in vivo. Here, we report a novel …

Gold derivatives development as prospective anticancer drugs for breast cancer treatment

I Ielo, D Iacopetta, C Saturnino, P Longo, M Galletta… - Applied Sciences, 2021 - mdpi.com
Commonly used anticancer drugs are cis platin and other platinum-based drugs. However,
the use of these drugs in chemotherapy causes numerous side effects and the onset of …