Synthesis, properties, and antitumor effects of a new mixed phosphine gold (I) compound in human colon cancer cells
G Lupidi, L Avenali, M Bramucci, L Quassinti… - Journal of Inorganic …, 2013 - Elsevier
The antineoplastic potential of a new stable mixed phosphine gold (I) complex containing
tris (tert-butyl) phosphine (tBu3P) and bis (diphenylphosphino) ethene (dppet), namely [Au …
tris (tert-butyl) phosphine (tBu3P) and bis (diphenylphosphino) ethene (dppet), namely [Au …
Mechanistic studies on two dinuclear organogold(iii) compounds showing appreciable antiproliferative properties and a high redox stability
Two dinuclear oxo-bridged organogold (iii) compounds, namely [(N, N, C) 2Au2 (μ-O)][PF6]
2 (with N, N, CH= 6-(1-methylbenzyl)-2, 2′-bipyridine, Au22O1; or 6-(1, 1-dimethylbenzyl) …
2 (with N, N, CH= 6-(1-methylbenzyl)-2, 2′-bipyridine, Au22O1; or 6-(1, 1-dimethylbenzyl) …
Anti-cancer potential of gold complexes
ERT Tiekink - Inflammopharmacology, 2008 - Springer
A full range of gold compounds is currently being investigated for their potential as anti-
tumor agents. Gold (I) compounds related to the anti-arthritic drug\rm Auranofin^\circledR …
tumor agents. Gold (I) compounds related to the anti-arthritic drug\rm Auranofin^\circledR …
Gold organometallics with biological properties
This chapter compiles advances in the investigation of the biological properties of gold
organometallic compounds with possible therapeutic applications, in particular as …
organometallic compounds with possible therapeutic applications, in particular as …
In vivo anticancer activity, toxicology and histopathological studies of the thiolate gold (I) complex [Au (Spyrimidine)(PTA-CH2Ph)] Br
E García-Moreno, S Gascón… - Anti-Cancer Agents …, 2015 - ingentaconnect.com
A physiologically stable thiolate gold (I) derivative [Au (Spyrimidine)(PTA-CH2Ph)] Br has
shown inhibition in colon cancer proliferation of Caco-2/TC7, Caco-2/PD7 and HTC-116 …
shown inhibition in colon cancer proliferation of Caco-2/TC7, Caco-2/PD7 and HTC-116 …
Gold (I/III)-phosphine complexes as potent antiproliferative agents
The reaction of gold reagents [HAuCl4• 3H2O],[AuCl (tht)], or cyclometalated gold (III)
precursor,[C^ NAuCl2] with chiral ((R, R)-(-)-2, 3-bis (t-butylmethylphosphino) quinoxaline) …
precursor,[C^ NAuCl2] with chiral ((R, R)-(-)-2, 3-bis (t-butylmethylphosphino) quinoxaline) …
Mass spectrometry uncovers molecular reactivities of coordination and organometallic gold (III) drug candidates in competitive experiments that correlate with their …
SM Meier, C Gerner, BK Keppler, MA Cinellu… - Inorganic …, 2016 - ACS Publications
The reactivity of three cytotoxic organometallic gold (III) complexes with cyclometalated C, N,
N and C, N ligands (either six-or five-membered metallacycles), as well as that of two …
N and C, N ligands (either six-or five-membered metallacycles), as well as that of two …
Gold (III) complexes as potential antitumor agents: solution chemistry and cytotoxic properties of some selected gold (III) compounds
Gold (III) complexes generally exhibit interesting cytotoxic and antitumor properties, but until
now, their development has been heavily hampered by their poor stability under …
now, their development has been heavily hampered by their poor stability under …
A soluble bis-chelated gold (I) diphosphine compound with strong anticancer activity and low toxicity
Y Wang, M Liu, R Cao, W Zhang, M Yin… - Journal of Medicinal …, 2013 - ACS Publications
Gold-containing compounds have shown anticancer potential, but their clinical applications
have been severely limited by poor stability and high toxicity in vivo. Here, we report a novel …
have been severely limited by poor stability and high toxicity in vivo. Here, we report a novel …
Gold derivatives development as prospective anticancer drugs for breast cancer treatment
Commonly used anticancer drugs are cis platin and other platinum-based drugs. However,
the use of these drugs in chemotherapy causes numerous side effects and the onset of …
the use of these drugs in chemotherapy causes numerous side effects and the onset of …