It has been recently reported that cigarette smoke exposure during allergen sensitization
facilitates the development of allergic asthma; however, the underlying mechanisms remain …

Air pollutant exposure leads to and exacerbates respiratory diseases. Particulate Matter
(PM) is a major deleterious factor in the pathophysiology of asthma. Nonetheless, studies on …

Interleukin 23 and the interleukin 23 receptor (IL-23-IL23R) are described as the major
enhancing factors for Interleukin 17 (IL-17) in allergic airway inflammation. IL-17 is …

IL-23 has been postulated to be a critical mediator contributing to various inflammatory
diseases. Dermatophagoides pteronyssinus (Der p) is one of the most common inhalant …

There is evidence that IL-22 and IL-17 participate in the pathogenesis of allergic asthma. To
investigate the role of IL-22, we used IL-22 deficient mice (IL-22 KO) sensitized and …

Background: Interleukin (IL)-23/Th17 axis plays an important role in the pathophysiology of
asthma and eczema, however, there are some conflicting data about the effects of this …

IL-22 is a Th17/Th22 cytokine that is increased in asthma. However, recent animal studies
showed controversial findings in the effects of IL-22 in allergic asthma. To determine the role …

Cigarette smoke (CS) facilitates adverse effects on the airway inflammation and treatment of
asthma. Here, we investigated the mechanisms by which CS exacerbates asthma. The roles …

abstract Background: The role of interleukin (IL)-23 in asthma pathophysiology is still
controversial. We examined its role in allergic airway inflammation in response to two …

It has been recently that particulate matter (PM) exposure increases the risk and
exacerbation of allergic asthma. However, the underlying mechanisms and factors …