Identification of two functional regions in Fis: the N‐terminus is required to promote Hin‐mediated DNA inversion but not lambda excision.

R Osuna, SE Finkel, RC Johnson - The EMBO Journal, 1991 - embopress.org
The Fis protein of E. coli binds to a recombinational enhancer sequence that is required to
stimulate Hin‐mediated DNA inversion. Fis is also required for efficient lambda prophase …

Location, degree, and direction of DNA bending associated with the Hin recombinational enhancer sequence and Fis-enhancer complex

D Perkins-Balding, DP Dias… - Journal of bacteriology, 1997 - Am Soc Microbiol
The Fis protein of Escherichia coli and Salmonella typhimurium stimulates several site-
specific DNA recombination reactions, as well as transcription of a number of genes. Fis …

The N-terminal part of the E.Coli DNA binding protein FIS is essential for stimulating site-specific DNA inversion but is not required for specific DNA …

C Koch, O Ninnemann, H Fuss… - Nucleic acids …, 1991 - academic.oup.com
FIS protein is involved in several different cellular processes stimulating site-specific
recombination in phages Mu and λ as well as transcription of stable RNA operons in E. coli …

The molecular structure of wild-type and a mutant Fis protein: relationship between mutational changes and recombinational enhancer function or DNA binding.

HS Yuan, SE Finkel, JA Feng… - Proceedings of the …, 1991 - National Acad Sciences
The 98-amino acid Fis protein from Escherichia coli functions in a variety of reactions,
including promotion of Hin-mediated site-specific DNA inversion when bound to an …

Fis binding to the recombinational enhancer of the Hin DNA inversion system.

MF Bruist, AC Glasgow, RC Johnson… - Genes & …, 1987 - genesdev.cshlp.org
The recombinational enhancer of the Hin inversion system in Salmonella stimulates
recombination in vitro 150-fold in the presence of the Escherichia coli host factor Fis. To gain …

[HTML][HTML] The Hin dimer interface is critical for Fis-mediated activation of the catalytic steps of site-specific DNA inversion

MJ Haykinson, LM Johnson, J Soong, RC Johnson - Current Biology, 1996 - cell.com
Background: Hin is a member of an extended family of site-specific recombinases–the DNA
invertase/resolvase family–that catalyze inversion or deletion of DNA. DNA inversion by Hin …

The FIS protein binds and bends the origin of chromosomal DNA replication, oriC, of Escherichia coli

H Gille, JB Egan, A Roth, W Messer - Nucleic acids research, 1991 - academic.oup.com
The FIS protein (factor for inversion stimulation) is known to stimulate site-specific
recombination processes, such as the inversion of the G segment of bacteriophage Mu, by …

Bent DNA is needed for recombinational enhancer activity in the site-specific recombination system cin of bacteriophage P1 the role of FIS protein

P Hübner, P Haffter, S Iida, W Arber - Journal of molecular biology, 1989 - Elsevier
A series of recombinational enhancer mutants was constructed by manipulating the ClaI site
between the two FIS binding sites of the Hin enhancer. These mutants include insertions …

Intermediates in Hin‐mediated DNA inversion: a role for Fis and the recombinational enhancer in the strand exchange reaction.

RC Johnson, MF Bruist - The EMBO Journal, 1989 - embopress.org
The site‐specific inversion reaction controlling flagellin synthesis in Salmonella involves the
function of three proteins: Hin, Fis and HU. The DNA substrate must be supercoiled and …

Isolation of the gene encoding the Hin recombinational enhancer binding protein.

RC Johnson, CA Ball, D Pfeffer… - Proceedings of the …, 1988 - National Acad Sciences
In vitro DNA inversion mediated by the protein Hin requires the presence of a
recombinational enhancer sequence located in cis relative to the recombination sites and a …