Sex differences in the association between AD biomarkers and cognitive decline

MEI Koran, M Wagener, TJ Hohman… - Brain imaging and …, 2017 - Springer
Women are disproportionately affected by Alzheimer's disease (AD) in terms of both disease
prevalence and severity. Previous autopsy work has suggested that, in the presence of AD …

Sex differences in cognitive decline in subjects with high likelihood of mild cognitive impairment due to Alzheimer's disease

D Sohn, K Shpanskaya, JE Lucas, JR Petrella… - Scientific reports, 2018 - nature.com
Sex differences in Alzheimer's disease (AD) biology and progression are not yet fully
characterized. The goal of this study is to examine the effect of sex on cognitive progression …

Gender differences in Alzheimer disease: brain atrophy, histopathology burden, and cognition

JR Filon, AJ Intorcia, LI Sue… - … of Neuropathology & …, 2016 - academic.oup.com
Multiple studies suggest that females are affected by Alzheimer disease (AD) more severely
and more frequently than males. Other studies have failed to confirm this and the issue …

Does the female advantage in verbal memory contribute to underestimating Alzheimer's disease pathology in women versus men?

EE Sundermann, A Biegon, LH Rubin… - Journal of …, 2017 - content.iospress.com
There is a growing recognition of sex differences in Alzheimer's disease (AD). Females
show an advantage over males on tests of verbal memory, which are used to diagnose AD …

Increased Alzheimer's risk during the menopause transition: a 3-year longitudinal brain imaging study

L Mosconi, A Rahman, I Diaz, X Wu, O Scheyer… - PloS one, 2018 - journals.plos.org
Two thirds of all persons with late-onset Alzheimer's disease (AD) are women. Identification
of sex-based molecular mechanisms underpinning the female-based prevalence of AD …

Female specific risk factors for the development of Alzheimer's disease neuropathology and cognitive impairment: Call for a precision medicine approach

C Udeh-Momoh, T Watermeyer - Ageing Research Reviews, 2021 - Elsevier
Alzheimer's disease (AD) includes a long asymptomatic stage, which precedes the formal
diagnosis of dementia. AD biomarker models provide a framework for precision medicine …

Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints

E Cavedo, PA Chiesa, M Houot, MT Ferretti… - Alzheimer's & …, 2018 - Elsevier
Introduction Observational multimodal neuroimaging studies indicate sex differences in
Alzheimer's disease pathophysiological markers. Methods Positron emission tomography …

Sex differences in Alzheimer's disease and common neuropathologies of aging

S Oveisgharan, Z Arvanitakis, L Yu, J Farfel… - Acta …, 2018 - Springer
Alzheimer's dementia is significantly more common in women than in men. However, few
pathological studies have addressed sex difference in Alzheimer's disease (AD) and other …

Sex difference in Alzheimer's disease: An updated, balanced and emerging perspective on differing vulnerabilities

DB Dubal - Handbook of clinical neurology, 2020 - Elsevier
Sex biology influences Alzheimer's disease (AD). Sex differences exist in the epidemiologic,
imaging, biomarker, and pathology studies of this uniquely human condition. The mandate …

Menopause status moderates sex differences in tau burden: a Framingham PET study

RF Buckley, A O'Donnell, ER McGrath… - Annals of …, 2022 - Wiley Online Library
Objective Women have a higher lifetime risk of Alzheimer's disease (AD) than men. Among
cognitively normal (CN) older adults, women exhibit elevated tau positron emission …