The element gallium, although it has no known trace element function, interacts with
biological systems in many unique ways. When administered intravenously at low levels in …

Previous studies of the effect of scandium on the tissue distribution of Ga-67 suggest that Ga-
67 makes its initial in vivo entry into normal and malignant tissues by different …

Two cultured mouse tumour cell lines, HPC-108 (myeloma) and WEHI-22 (T lymphoma),
were used in an investigation of transferrin promotion of 67 Ga. and 59 Fe uptake by …

After almost two decades of research, evidence suggests that transferrin receptors are rate-
limiting in 67Ga uptake. 67Ga imaging is an in vivo detector of transferrin receptors and an …

DISCUSSION Although poorly understood in the past, much has been learned about the
metabolism of gallium and similar ions in recent years (5— 12). Studieshave shown that …

The present study was undertaken to elucidate the accumulation mechanism of gallium 67
in inflammatory tissue. 67 Ga accumulation in inflammatory tissue was observed by macro …

Ga—67 to Human Transferrin Page 1 Ga—67 to Human Transferrin Steven M. Larson, David
R.Allen, Janet S. Rasey, and Zdenka Grunbaum Veterans Administration Hospital and the …

P-glycoprotein (ABCB1) is expressed at the blood–retina barrier (BRB), where it may control
distribution of drugs from blood to the retina and thereby influence drug efficacy and toxicity …

The EMT-6 sarcoma-like tumor of BALBIc mice can be grown as a solid subcuta neous
transplantable tumor in vivo or as a monolayer culture in vitro. We have studied the uptake of …

We studied the tumor uptake of [67Ga] citrate,[59Fe] citrate, and 125I-labeled transferrin (TF)
by the in vitro growth form of EMT-6, a sarcoma-like mammary tumor of BALB/c mice. In …