Differential toxicity of sulfur mustard administered through percutaneous, subcutaneous, and oral routes

R Vijayaraghavan, A Kulkarni, SC Pant, P Kumar… - Toxicology and applied …, 2005 - Elsevier
Sulfur mustard (SM), chemically 2, 2′-dichloro diethyl sulphide, is an incapacitating and
extremely toxic chemical warfare agent. It causes serious blisters on contact with human …

Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts

S Inturi, N Tewari-Singh, M Gu, S Shrotriya… - Free Radical Biology …, 2011 - Elsevier
Employing mouse skin epidermal JB6 cells and dermal fibroblasts, here we examined the
mechanisms of DNA damage by 2-chloroethyl ethyl sulfide (CEES), a monofunctional …

N-Acetyl-l-Cysteine as Prophylaxis against Sulfur Mustard

AJ Bobb, DP Arfsten, WW Jederberg - Military medicine, 2005 - academic.oup.com
Sulfur mustard (HD) is a blister agent targeting the eyes, respiratory system, skin, and
possibly other organs. Extensive exposure can destroy the immune system by destruction of …

Cutaneous and ocular late complications of sulfur mustard in Iranian veterans

M Shohrati, M Davoudi, M Ghanei… - … and ocular toxicology, 2007 - Taylor & Francis
Although sulfur mustard (SM) has been used as a chemical warfare agent since the early
twentieth century, it has reemerged in the past decade as a major threat around the world …

Sulphur mustard induced DNA damage in mice after dermal and inhalation exposure

PVL Rao, R Vijayaraghavan, ASB Bhaskar - Toxicology, 1999 - Elsevier
Sulphur mustard (SM) is a chemical warfare agent of the blistering agent category for which
there is still no effective therapy. SM, being a strong electrophile, readily reacts with a wide …

Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect

DR Gerecke, M Chen, SS Isukapalli, MK Gordon… - Toxicology and applied …, 2009 - Elsevier
Sulfur mustard (HD, SM), is a chemical warfare agent that within hours causes extensive
blistering at the dermal–epidermal junction of skin. To better understand the progression of …

Diagnosis and dosimetry of exposure to sulfur mustard: development of a standard operating procedure for mass spectrometric analysis of haemoglobin adducts …

D Noort, A Fidder, AG Hulst… - Journal of applied …, 2000 - Wiley Online Library
Experiments were carried out to develop a standard operating procedure for analysis of
sulfur mustard adducts to the N‐terminal valine in haemoglobin and to explore adduct …

Amelioration of sulfur mustard skin injury following a topical treatment with a mixture of a steroid and a NSAID

S Dachir, E Fishbeine, Y Meshulam… - Journal of Applied …, 2004 - Wiley Online Library
The ability to ameliorate sulfur mustard (HD)‐induced oedema by treatment with anti‐
inflammatory drugs was reported previously after screening four steroids and four non …

Immunobiological consequences of sulfur mustard contamination

HZ MOHAMMAD, M Ebtekar, M Ghaneei, M Taghikhani… - 2006 - sid.ir
Sulfur mustard has been employed in CHEMICAL WARFARE in certain regions including
Iran. The short and long term biological effects of SULFUR MUSTARD contamination have …

Detection of sulfur mustard-induced DNA modifications

DB Ludlum, P Austin-Ritchie, M Hagopian… - Chemico-biological …, 1994 - Elsevier
Sulfur mustard is acutely toxic to the skin, eyes, and respiratory tract, and is considered
carcinogenic to humans by the IARC. Since all of these toxicities are thought to be initiated …