Cutaneous toxicity of 2-chloroethyl methyl sulfide in isolated perfused porcine skin

JR King, NA Monteiro-Riviere - Toxicology and applied pharmacology, 1990 - Elsevier
Previous research has shown the isolated perfused porcine skin flap (IPPSF) to be a novel
in vitro experimental model for investigating xenobiotic percutaneous absorption. In this …

Response of normal human keratinocytes to sulfur mustard (HD): cytokine release using a non-enzymatic detachment procedure

CM Arroyo, RJ Schafer, EM Kurt… - Human & …, 1999 - journals.sagepub.com
Cytokines play a major role in both acute and chronic inflammatory processes, including
those produced by sulfur mustard (HD). This study describes responses of normal human …

Ocular effects of sulfur mustard and therapeutic approaches

Y Panahi, SM Rajaee… - Journal of cellular …, 2017 - Wiley Online Library
Sulfur mustard (SM) is a strong blistering, highly reactive, lipophilic chemical war agent that
causes injury in different organs including the skin, eyes, and respiratory tract. The Eyes are …

Toxicodynamics of sulfur mustard.

SM Somani, SR Babu - International journal of clinical …, 1989 - europepmc.org
Mustards have become an important topic of global discussion in recent years. The latest
extensive reports and conference of 145 nations in Paris (January 13, 1989) reveal that …

Chronic health effects of sulphur mustard exposure with special reference to Iranian veterans

M Balali-Mood, SH Mousavi… - Emerging health threats …, 2008 - Taylor & Francis
The widespread use of sulphur mustard (SM) as an incapacitating chemical warfare agent in
the past century has proved its long-lasting toxic effects. It may also be used as a chemical …

Mustard vesicating agent–induced toxicity in the skin tissue and silibinin as a potential countermeasure

N Tewari‐Singh, R Agarwal - Annals of the New York Academy …, 2016 - Wiley Online Library
Exposure to the vesicating agents sulfur mustard (SM) and nitrogen mustard (NM) causes
severe skin injury with delayed blistering. Depending upon the dose and time of their …

Microarray analysis of gene expression in murine skin exposed to sulfur mustard

JV Rogers, YW Choi, RC Kiser… - … of Biochemical and …, 2005 - Wiley Online Library
The chemical warfare agent sulfur mustard [bis‐(2‐chloroethyl)‐sulfide; SM] produces a
delayed inflammatory response followed by blister formation in skin of exposed individuals …

[HTML][HTML] Role of NF-κB/RelA and MAPK pathways in keratinocytes in response to sulfur mustard

B Rebholz, K Kehe, T Ruzicka, RA Rupec - Journal of investigative …, 2008 - Elsevier
Sulfur mustard (SM) is a strong vesicant that has been used as a chemical warfare agent. To
understand the molecular mechanisms that underlie the inflammatory skin reaction in …

Toxicology and pharmacology of the chemical warfare agent sulfur mustard.

JC Dacre, M Goldman - Pharmacological reviews, 1996 - ASPET
There have been reports of chemical attacks in which sulfur mustard might have been used
(a) on Iranian soldiers and civilians during the Gulf War in 1984 and 1985 and (b) in an Iraqi …

Potential anti-inflammatory treatments against cutaneous sulfur mustard injury using the mouse ear vesicant model

S Dachir, E Fishbeine, Y Meshulam… - Human & …, 2002 - journals.sagepub.com
In spite of several decades of research, no effective treatment to skin injuries following
exposure to sulfur mustard (HD) has yet been found. In the present study, the mouse ear …