Bone replaces articular cartilage in the rat knee joint after prolonged immobilization
TM Campbell, K Reilly, O Laneuville, H Uhthoff… - Bone, 2018 - Elsevier
Background Lost joint range of motion (ROM) is common in chronic osteoarthritis, alters
regional weight-bearing across the articular surfaces, and contributes to loss of cartilage and …
regional weight-bearing across the articular surfaces, and contributes to loss of cartilage and …
Meniscal and articular cartilage changes in knee osteoarthritis: a cross‐sectional double‐contrast macroradiographic study
LD Bennett, JC Buckland‐Wright - Rheumatology, 2002 - academic.oup.com
Objective. In knee osteoarthritis (OA) damage to meniscal cartilage is associated with the
changes in articular cartilage. Using double‐contrast macroradiographs we determined …
changes in articular cartilage. Using double‐contrast macroradiographs we determined …
Joint instability and OA: do animal models provide insights?
KPH Pritzker - Nature Reviews Rheumatology, 2011 - nature.com
Joint injury represents a major risk factor for the development of osteoarthritis, but a link
between severity of injury and the level of cartilage damage is difficult to test in humans …
between severity of injury and the level of cartilage damage is difficult to test in humans …
Modeling and staging of osteoarthritis progression using serial CT imaging and arthroscopy
C Flynn, M Hurtig, E Lamoure, E Cummins… - Cartilage, 2020 - journals.sagepub.com
Objective The objective of this study was to describe in life methods by which osteoarthritis
can be staged in order to time therapeutic interventions that are relevant to osteoarthritis …
can be staged in order to time therapeutic interventions that are relevant to osteoarthritis …
Towards understanding mechanistic subgroups of osteoarthritis: 8‐year cartilage thickness trajectory analysis
Many studies have validated cartilage thickness as a biomarker for knee osteoarthritis (OA);
however, few studies investigate beyond cross‐sectional observations or comparisons …
however, few studies investigate beyond cross‐sectional observations or comparisons …
[HTML][HTML] The degeneration and destruction of femoral articular cartilage shows a greater degree of deterioration than that of the tibial and patellar articular cartilage in …
S Hada, H Kaneko, R Sadatsuki, L Liu, I Futami… - Osteoarthritis and …, 2014 - Elsevier
Objective The aim of the present study was to examine whether the degenerative and
morphological changes of articular cartilage in early stage knee osteoarthritis (OA) occurred …
morphological changes of articular cartilage in early stage knee osteoarthritis (OA) occurred …
Abnormal tibiofemoral kinematics following ACL reconstruction are associated with early cartilage matrix degeneration measured by MRI T1rho
B Haughom, W Schairer, RB Souza, D Carpenter… - The Knee, 2012 - Elsevier
PURPOSE: Altered kinematics following ACL-reconstruction may be a cause of post-
traumatic osteoarthritis. T1ρ MRI is a technique that detects early cartilage matrix …
traumatic osteoarthritis. T1ρ MRI is a technique that detects early cartilage matrix …
Analysis of the articular cartilage T1ρ and T2 relaxation times changes after ACL reconstruction in injured and contralateral knees and relationships with bone shape
The objectives of this study were twofold:(1) to evaluate the longitudinal change in cartilage
T1ρ and T2 6‐and 12‐months after ACL reconstruction (ACLR) in both reconstructed and …
T1ρ and T2 6‐and 12‐months after ACL reconstruction (ACLR) in both reconstructed and …
[HTML][HTML] The acute structural changes of loaded articular cartilage following meniscectomy or ACL-transection
Objective Meniscectomy and anterior cruciate ligament (ACL) rupture have been identified
as precursors of osteoarthrosis (OA) in clinical reviews and animal experiments. In this …
as precursors of osteoarthrosis (OA) in clinical reviews and animal experiments. In this …
[HTML][HTML] Radiographically normal knees with contralateral joint space narrowing display greater change in cartilage transverse relaxation time than those with normal …
Objective To develop a model of early osteoarthritis, by examining whether radiographically
normal knees with contralateral joint space narrowing (JSN), but without contralateral …
normal knees with contralateral joint space narrowing (JSN), but without contralateral …