Bone replaces articular cartilage in the rat knee joint after prolonged immobilization

TM Campbell, K Reilly, O Laneuville, H Uhthoff… - Bone, 2018 - Elsevier
Background Lost joint range of motion (ROM) is common in chronic osteoarthritis, alters
regional weight-bearing across the articular surfaces, and contributes to loss of cartilage and …

Meniscal and articular cartilage changes in knee osteoarthritis: a cross‐sectional double‐contrast macroradiographic study

LD Bennett, JC Buckland‐Wright - Rheumatology, 2002 - academic.oup.com
Objective. In knee osteoarthritis (OA) damage to meniscal cartilage is associated with the
changes in articular cartilage. Using double‐contrast macroradiographs we determined …

Joint instability and OA: do animal models provide insights?

KPH Pritzker - Nature Reviews Rheumatology, 2011 - nature.com
Joint injury represents a major risk factor for the development of osteoarthritis, but a link
between severity of injury and the level of cartilage damage is difficult to test in humans …

Modeling and staging of osteoarthritis progression using serial CT imaging and arthroscopy

C Flynn, M Hurtig, E Lamoure, E Cummins… - Cartilage, 2020 - journals.sagepub.com
Objective The objective of this study was to describe in life methods by which osteoarthritis
can be staged in order to time therapeutic interventions that are relevant to osteoarthritis …

Towards understanding mechanistic subgroups of osteoarthritis: 8‐year cartilage thickness trajectory analysis

C Iriondo, F Liu, F Calivà, S Kamat… - Journal of …, 2021 - Wiley Online Library
Many studies have validated cartilage thickness as a biomarker for knee osteoarthritis (OA);
however, few studies investigate beyond cross‐sectional observations or comparisons …

[HTML][HTML] The degeneration and destruction of femoral articular cartilage shows a greater degree of deterioration than that of the tibial and patellar articular cartilage in …

S Hada, H Kaneko, R Sadatsuki, L Liu, I Futami… - Osteoarthritis and …, 2014 - Elsevier
Objective The aim of the present study was to examine whether the degenerative and
morphological changes of articular cartilage in early stage knee osteoarthritis (OA) occurred …

Abnormal tibiofemoral kinematics following ACL reconstruction are associated with early cartilage matrix degeneration measured by MRI T1rho

B Haughom, W Schairer, RB Souza, D Carpenter… - The Knee, 2012 - Elsevier
PURPOSE: Altered kinematics following ACL-reconstruction may be a cause of post-
traumatic osteoarthritis. T1ρ MRI is a technique that detects early cartilage matrix …

Analysis of the articular cartilage T and T2 relaxation times changes after ACL reconstruction in injured and contralateral knees and relationships with bone shape

V Pedoia, F Su, K Amano, Q Li… - Journal of …, 2017 - Wiley Online Library
The objectives of this study were twofold:(1) to evaluate the longitudinal change in cartilage
T1ρ and T2 6‐and 12‐months after ACL reconstruction (ACLR) in both reconstructed and …

[HTML][HTML] The acute structural changes of loaded articular cartilage following meniscectomy or ACL-transection

MJ Kääb, K Ito, JM Clark, HP Nötzli - Osteoarthritis and cartilage, 2000 - Elsevier
Objective Meniscectomy and anterior cruciate ligament (ACL) rupture have been identified
as precursors of osteoarthrosis (OA) in clinical reviews and animal experiments. In this …

[HTML][HTML] Radiographically normal knees with contralateral joint space narrowing display greater change in cartilage transverse relaxation time than those with normal …

W Wirth, S Maschek, FW Roemer, L Sharma… - Osteoarthritis and …, 2019 - Elsevier
Objective To develop a model of early osteoarthritis, by examining whether radiographically
normal knees with contralateral joint space narrowing (JSN), but without contralateral …