Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk

P Fusar-Poli, I Bonoldi, AR Yung… - Archives of general …, 2012 - jamanetwork.com
Context A substantial proportion of people at clinical high risk of psychosis will develop a
psychotic disorder over time. However, the risk of transition to psychosis varies between …

Probability of transition to psychosis in individuals at clinical high risk: an updated meta-analysis

GS De Pablo, J Radua, J Pereira, I Bonoldi… - JAMA …, 2021 - jamanetwork.com
Importance Estimating the current likelihood of transitioning from a clinical high risk for
psychosis (CHR-P) to psychosis holds paramount importance for preventive care and …

Predictors of transition in patients with clinical high risk for psychosis: an umbrella review

C Andreou, S Eickhoff, M Heide, R de Bock… - Translational …, 2023 - nature.com
Diagnosis of a clinical high-risk (CHR) state enables timely treatment of individuals at risk for
a psychotic disorder, thereby contributing to improving illness outcomes. However, only a …

Moving beyond transition outcomes: meta-analysis of remission rates in individuals at high clinical risk for psychosis

AE Simon, S Borgwardt, A Riecher-Rössler… - Psychiatry …, 2013 - Elsevier
Recent evidence suggests that transition risks from initial clinical high risk (CHR) status to
psychosis are decreasing. The role played by remission in this context is mostly unknown …

Clinical outcomes in individuals at clinical high risk of psychosis who do not transition to psychosis: a meta-analysis

GS De Pablo, L Soardo, A Cabras, J Pereira… - Epidemiology and …, 2022 - cambridge.org
Aims The clinical outcomes of individuals at clinical high risk of psychosis (CHR-P) who do
not transition to psychosis are heterogeneous and inconsistently reported. We aimed to …

What causes the onset of psychosis in individuals at clinical high risk? A meta-analysis of risk and protective factors

D Oliver, TJ Reilly, O Baccaredda Boy… - Schizophrenia …, 2020 - academic.oup.com
Twenty percent of individuals at clinical high risk for psychosis (CHR-P) develop the disorder
within 2 years. Extensive research has explored the factors that differentiate those who …

Prediction of transition to psychosis in patients with a clinical high risk for psychosis: a systematic review of methodology and reporting

E Studerus, A Ramyead… - Psychological medicine, 2017 - cambridge.org
BackgroundTo enhance indicated prevention in patients with a clinical high risk (CHR) for
psychosis, recent research efforts have been increasingly directed towards estimating the …

At clinical high risk for psychosis: outcome for nonconverters

J Addington, BA Cornblatt… - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: A major focus of early intervention research is determining the risk of conversion
to psychosis and developing optimal algorithms of prediction. Although reported rates of …

Early-onset of symptoms predicts conversion to non-affective psychosis in ultra-high risk individuals

GP Amminger, S Leicester, AR Yung, LJ Phillips… - Schizophrenia …, 2006 - Elsevier
OBJECTIVE: We examined if age of onset of psychiatric symptoms and/or sex predict
conversion to non-affective or affective psychosis in individuals considered to be at ultra …

Risk factors for transition to first episode psychosis among individuals with 'at-risk mental states'

O Mason, M Startup, S Halpin, U Schall, A Conrad… - Schizophrenia …, 2004 - Elsevier
Recently developed criteria have been successful at identifying individuals at imminent risk
of developing a psychotic disorder, but these criteria lead to 50–60% false positives. This …