Sulfur mustard exposure enhances Fc receptor expression on human epidermal keratinocytes in cell culture: implications for toxicity and medical countermeasures
FM Cowan, CA Broomfield, WJ Smith - Cell biology and toxicology, 1998 - Springer
Sulfur mustard (HD) is a chemical warfare blister agent. The biochemical basis of HD-
induced vesication is unknown, and no antidote currently exists. Basal epidermal cells are a …
induced vesication is unknown, and no antidote currently exists. Basal epidermal cells are a …
Exposure of human epidermal keratinocyte cell cultures to sulfur mustard promotes binding of complement C1q: implications for toxicity and medical countermeasures
FM Cowan, CA Broomfield… - Journal of applied …, 2000 - Wiley Online Library
Sulfur mustard (HD)‐increased proteolytic activity, HD‐enhanced expression of Fc receptor
(FcR) on human epidermal keratinocytes (HEK) and associated inflammatory responses …
(FcR) on human epidermal keratinocytes (HEK) and associated inflammatory responses …
Development of a co-culture of keratinocytes and immune cells for in vitro investigation of cutaneous sulfur mustard toxicity
F Balszuweit, G Menacher, B Bloemeke… - Chemico-biological …, 2014 - Elsevier
Sulfur mustard (SM) is a chemical warfare agent causing skin blistering, ulceration and
delayed wound healing. Inflammation and extrinsic apoptosis are known to have an …
delayed wound healing. Inflammation and extrinsic apoptosis are known to have an …
Sulfur mustard primes phagocytosis and degranulation in human polymorphonuclear leukocytes
AK Vavra, CJ Laurent, V Ngo, JF Sweeney… - International …, 2004 - Elsevier
Sulfur mustard (2, 2′-bis-chloroethyl-sulfide; SM) is a chemical warfare vesicant that
causes debilitating skin lesions. Although a great deal of work has focused on the direct …
causes debilitating skin lesions. Although a great deal of work has focused on the direct …
Sulfur mustard induces immune sensitization in hairless guinea pigs
NC Mishra, T March, W Weber, J Benson… - International …, 2010 - Elsevier
Sulfur mustard (SM, bis-(2-chloroethyl) sulfide) is a well known chemical warfare agent that
may cause long-term debilitating injury. Because of the ease of production and storage, it …
may cause long-term debilitating injury. Because of the ease of production and storage, it …
Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposure
Sulfur mustard (SM), a chemical weapon first employed during World War I, targets the skin,
eyes, and lung. It remains a significant military and civilian threat. The characteristic …
eyes, and lung. It remains a significant military and civilian threat. The characteristic …
Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect
DR Gerecke, M Chen, SS Isukapalli, MK Gordon… - Toxicology and applied …, 2009 - Elsevier
Sulfur mustard (HD, SM), is a chemical warfare agent that within hours causes extensive
blistering at the dermal–epidermal junction of skin. To better understand the progression of …
blistering at the dermal–epidermal junction of skin. To better understand the progression of …
Suppression of sulfur mustard-increased IL-8 in human keratinocyte cell cultures by serine protease inhibitors: implications for toxicity and medical countermeasures
FM Cowan, CA Broomfield, WJ Smith - Cell biology and toxicology, 2002 - Springer
The toxicity of the chemical warfare blistering agent sulfur mustard (2, 2'-dichlorodiethyl
sulfide; SM) has been investigated for nearly a century; however, the toxicological …
sulfide; SM) has been investigated for nearly a century; however, the toxicological …
Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl …
Sulfur mustard is a potent vesicant that induces inflammation, edema and blistering
following dermal exposure. To assess molecular mechanisms mediating these responses …
following dermal exposure. To assess molecular mechanisms mediating these responses …
Intervention of sulfur mustard toxicity by downregulation of cell proliferation and metabolic rates
R Ray, BJ Benton, DR Anderson… - Journal of applied …, 2000 - Wiley Online Library
Metabolically active and proliferating basal cells in the skin are most sensitive to the potent
skin blistering chemical warfare compound HD (bis‐(2‐chloroethyl) sulfide). We previously …
skin blistering chemical warfare compound HD (bis‐(2‐chloroethyl) sulfide). We previously …
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