Objective: Dramatic improvements in clinical symptoms of rheumatoid arthritis and ulcerative
colitis were observed after patients received granulocyte and monocyte adsorptive …

Granulocyte and monocyte adsorptive apheresis (GMA) using a column filled with cellulose
acetate (CA) beads (carriers) has been associated with a significant clinical efficacy in …

Our aim was to understand the mechanism of immunological changes associated with the
use of an adsorptive-type extracorporeal device (Adacolumn) that has been developed for …

Objective: Evolving evidence of anti-inflammatory effects is observed in patients with
rheumatoid arthritis or ulcerative colitis following periodic adsorptive granulocyte and …

We examined the effects of complement activation on the biological responses of cellulose
acetate (CA) beads. Peripheral blood containing the complement activation inhibitor …

To elucidate the molecular mechanisms involved in the therapeutic effects of
granulocyte/monocyte adsorption apheresis, changes were investigated in the cytokine …

Objective Apoptotic cells participate in maintenance of homeostasis of the adaptive immune
system. Granulocyte/monocyte adsorptive apheresis (GMA) performed with an Adacolumn …

Tumor necrosis factor‐α,(TNF)‐α, a proinflammatory cytokine, is produced by activated
granulocytes and monocytes (GMs) and implicated as a major factor in inflammatory bowel …

Apheresis has been recognized both economically and therapeuticallyas a novel approach
for the treatment of inflammatory diseases, and certain others, which respond poorly to drug …

BACKGROUND: Granulocyte and monocyte adsorptive apheresis (GMA) with an
Adacolumn has been reported to be effective as induction therapy in ulcerative colitis (UC) …