Non-coplanar beam intensity modulation allows large dose escalation in stage III lung cancer

S Derycke, B Van Duyse, W De Gersem… - Radiotherapy and …, 1997 - Elsevier
Purpose: To evaluate the feasibility of dose escalation in stage III non-small cell lung cancer,
we compared standard coplanar (2D) with non-coplanar beam arrangements, without (3D) …

Inhomogeneous target-dose distributions: A dimension more for optimization?

WRT De Gersem, S Derycke, CO Colle… - International Journal of …, 1999 - Elsevier
Purpose: To evaluate if the use of inhomogeneous target-dose distributions, obtained by 3D
conformal radiotherapy plans with or without beam intensity modulation, offers the possibility …

Optimization of beam weights in conformal radiotherapy planning of stage III non–small cell lung cancer: effects on therapeutic ratio

WRT De Gersem, S Derycke, C De Wagter… - International Journal of …, 2000 - Elsevier
Purpose: To evaluate the effects of beam weight optimization for 3D conformal radiotherapy
plans, with or without beam intensity modulation, in Stage III non–small cell lung cancer …

An evaluation of two techniques for beam intensity modulation in patients irradiated for stage III non-small cell lung cancer

JVS De Koste, P Voet, M Dirkx, J Van Meerbeeck… - Lung Cancer, 2001 - Elsevier
In locally advanced lung cancer, the use of high dose radiotherapy (RT) and/or concurrent
chemo-RT is associated with significant pulmonary and esophageal toxicity. Despite a 3D …

Beam angle optimization and reduction for intensity-modulated radiation therapy of non–small-cell lung cancers

HH Liu, M Jauregui, X Zhang, X Wang, L Dong… - International Journal of …, 2006 - Elsevier
Purpose: To optimize beam angles and reduce the number of beams used for intensity-
modulated radiation therapy (IMRT) of non–small-cell lung cancer (NSCLC). Methods and …

Conformal radiotherapy of stage III non–small cell lung cancer: a class solution involving non–coplanar intensity-modulated beams

S Derycke, WRT De Gersem, BBR Van Duyse… - International Journal of …, 1998 - Elsevier
Purpose: We developed a semiautomatic class solution to irradiate centrally located Stage III
non–small cell lung cancer (NSCLC), involving a beam intensity modulation technique and …

Dose heterogeneity in the target volume and intensity-modulated radiotherapy to escalate the dose in the treatment of non–small-cell lung cancer

M Schwarz, M Alber, JV Lebesque, BJ Mijnheer… - International Journal of …, 2005 - Elsevier
Purpose: To quantify the dose escalation achievable in the treatment of non-small-cell lung
cancer (NSCLC) by allowing dose heterogeneity in the target volume or using intensity …

Dose and volume reduction for normal lung using intensity-modulated radiotherapy for advanced-stage non–small-cell lung cancer

H Murshed, HH Liu, Z Liao, JL Barker, X Wang… - International Journal of …, 2004 - Elsevier
PURPOSE: To investigate dosimetric improvements with respect to tumor-dose conformity
and normal tissue sparing using intensity-modulated radiotherapy (IMRT) compared with …

Dose escalation of chart in non-small cell lung cancer: is three-dimensional conformal radiation therapy really necessary?

C McGibney, O Holmberg, B McClean… - International Journal of …, 1999 - Elsevier
Purpose: To evaluate, preclinically, the potential for dose escalation of continuous,
hyperfractionated, accelerated radiation therapy (CHART) for non small-cell lung cancer …

[HTML][HTML] Is a clinical target volume (CTV) necessary for locally advanced non-small cell lung cancer treated with intensity-modulated radiotherapy?—a dosimetric …

F Xia, L Zhou, X Yang, L Chu, X Zhang… - Journal of Thoracic …, 2017 - ncbi.nlm.nih.gov
Background The aim of this study was to determine the feasibility of omitting the clinical
target volume (CTV) in patients with locally advanced non-small cell lung cancer (NSCLC) …