Delta catenin (CTNND2) is an adhesive junction associated protein belonging to the family
of p120ct catenins. It is located on the short arm of chromosome 5, a region deleted in Cri-du …

BACKGROUND: Over 200 mouse genes are associated with neural tube defects (NTDs),
including Cecr2, the bromodomain‐containing subunit of the CERF chromatin remodeling …

Neural tube defects (NTDs), including both spina bifida and anencephaly, are common
human congenital malformations that appear to be etiologically heterogeneous (Holmes et …

Mutations in MECP2 cause the neurodevelopmental disorder Rett syndrome (RTT). The RTT
missense MECP2 R306C mutation prevents MeCP2 from interacting with the NCoR/histone …

The three-dimensional genome structure organized by CTCF is required for development.
Clinically identified mutations in CTCF have been linked to adverse developmental …

Early-onset epileptic encephalopathies (EOEE) affect cognitive, sensory, and motor
development. Genetic variations are among the identifiable primary causes of these …

KCTD1 plays crucial roles in regulating both the SHH and WNT/β-catenin signaling
pathways, which are essential for tooth development. The objective of this study was to …

Delta-catenin (CTNND2) is an adhesive junction associated protein belonging to the family
of p120 catenins. The human gene is located on the short arm of chromosome 5, the region …

Lysosomes are central organelles for cellular degradation and energy metabolism.
Neuronal ceroid lipofuscinoses (NCLs) are a group of the most common neurodegenerative …

Introduction KCTD15 encodes an oligomeric BTB domain protein reported to inhibit neural
crest formation through repression of Wnt/beta-catenin signalling, as well as transactivation …