Publisher Summary This chapter focuses on the methods of receptor identification for
receptors localized on the cell surface. Receptors play a key role in regulating cellular …

Pharmacologists have been interested in the characterization of receptors ever since Ehrlich
and Langley put forward the idea, at the beginning of this century, that inter-cellular chemical …

Receptors in the nervous system have been identified for a number of neurotransmitters
such as acetylcholine, dopamine, serotonin, glutamate, and many peptides. Within these …

In the past ten years, binding sites for more than two dozen neurotransmitters and hormones
have been identified. With the exception of the thyroid and steroid hormone receptors, all …

Recent developments in the molecular pharmacology of receptor signalling are reviewed.
Receptors and other signalling molecules belong to superfamilies characterized by …

This review provides a brief summary of certain recent advances in our understanding of
receptor regulation, signal transduction, and the diverse pathways by which receptor-ligand …

This is a time of “great expectations” in the field of hormone and neurotransmitter action.
Recent advances in our understanding of receptors have been so dramatic that we appear …

A major advance in the biological sciences in the past decade has been the biochemical
identification of cell membrane receptors. The existence of re ceptor substances on the …

In the last article in this series, Morley Hollenberg describes the pathophysiological and
therapeutic implications of the mechanisms of receptor regulation. Diseases which involve …