Fever-range hyperthermia enhances L-selectin-dependent adhesion of lymphocytes to vascular endothelium

WC Wang, LM Goldman, DM Schleider… - The Journal of …, 1998 - journals.aai.org
The L-selectin leukocyte adhesion molecule plays an important role in controlling leukocyte
extravasation in peripheral lymph nodes and at sites of tissue injury or infection. Although …

Fever-range hyperthermia stimulates alpha4beta7 integrin-dependent lymphocyte-endothelial adhesion

SS Evans, MD Bain, WC Wang - International journal of …, 2000 - Taylor & Francis
Migration of blood-borne lymphocytes into lymphoid tissues is initiated by the Lselectin and
alpha4beta7 integrin adhesion molecules. Previous studies have shown that L-selectin …

Fever-range hyperthermia dynamically regulates lymphocyte delivery to high endothelial venules

SS Evans, WC Wang, MD Bain, R Burd… - Blood, The Journal …, 2001 - ashpublications.org
Fever is associated with increased survival during acute infection, although its mechanism of
action is largely unknown. This study found evidence of an unexpectedly integrated …

Cytokine and adhesion molecule expression in primary human endothelial cells stimulated with fever-range hyperthermia

A Shah, E Unger, MD Bain, R Bruce… - International Journal …, 2002 - Taylor & Francis
Migration of blood-borne lymphocytes into lymphoid tissues and sites of inflammation is
initiated by vascular adhesion molecules and proinflammatory cytokines. Previous in vivo …

Conservation of IL‐6 trans‐signaling mechanisms controlling L‐selectin adhesion by fever‐range thermal stress

MM Appenheimer, RA Girard, Q Chen… - European journal of …, 2007 - Wiley Online Library
Fever is associated with improved survival during infection in endothermic and ectothermic
species although the protective mechanisms are largely undefined. Previous studies …

Impact of fever-range thermal stress on lymphocyte-endothelial adhesion and lymphocyte trafficking

MM Appenheimer, Q Chen, RA Girard… - Immunological …, 2005 - Taylor & Francis
The evolutionarily conserved febrile response has been associated with improved survival
during infection in endothermic and ectothermic species although its protective mechanism …

[PDF][PDF] Central role of IL-6 receptor signal-transducing chain gp130 in activation of L-selectin adhesion by fever-range thermal stress

Q Chen, WC Wang, R Bruce, H Li, DM Schleider… - Immunity, 2004 - cell.com
The physiological benefit of the febrile response is poorly understood. Here we show that
fever-range thermal stress enhances the function of the L-selectin lymphocyte homing …

[PDF][PDF] IL-6 trans-signaling: the heat is on

S Rose-John, MF Neurath - Immunity, 2004 - cell.com
The molecular consequence of the fever response has been illuminated by a recent study
showing that a temperature shift to 40° C resulted in increased leukocyte adhesion to tissue …

Thermal facilitation of lymphocyte trafficking involves temporal induction of intravascular ICAM-1

Q Chen, Q Chen, MM Appenheimer, JB Muhitch… - …, 2009 - Taylor & Francis
Objective: Fever is associated with improved survival, although its beneficial mechanisms
are poorly understood. Previous studies indicate that the thermal element of fever augments …

Dynamic control of lymphocyte trafficking by fever-range thermal stress

Q Chen, DT Fisher, SA Kucinska, WC Wang… - Cancer Immunology …, 2006 - Springer
Migration of blood-borne lymphocytes into tissues involves a tightly orchestrated sequence
of adhesion events. Adhesion molecules and chemokine receptors on the surface of …