Modifiable comorbidities associated with cognitive decline in Parkinson's disease

E Forbes, TF Tropea, S Mantri, SX Xie… - Movement Disorders …, 2021 - Wiley Online Library
Background Cognitive impairment (CI) is one of the most feared and debilitating
complications of PD. No therapy has been shown to slow or prevent CI in PD. Objective To …

Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease

D Weintraub, T Simuni, C Caspell‐Garcia… - Movement …, 2015 - Wiley Online Library
This study was undertaken to determine the prevalence and correlates of cognitive
impairment (CI) and neuropsychiatric symptoms (NPS) in early, untreated patients with …

Predictors of cognitive impairment in an early stage Parkinson's disease cohort

MTM Hu, K Szewczyk‐Królikowski… - Movement …, 2014 - Wiley Online Library
The impact of Parkinson's disease (PD) dementia is substantial and has major functional
and socioeconomic consequences. Early prediction of future cognitive impairment would …

Quality of life in young‐compared with late‐onset Parkinson's disease

MDW Knipe, MM Wickremaratchi… - Movement …, 2011 - Wiley Online Library
The impact of Parkinson's disease on quality of life may vary depending on age at onset. We
investigated the effect of age at onset on quality of life in a large Parkinson's disease …

Modifiable risk factors for cognitive impairment in Parkinson's disease: a systematic review and meta‐analysis of prospective cohort studies

Y Guo, W Xu, FT Liu, JQ Li, XP Cao, L Tan… - Movement …, 2019 - Wiley Online Library
Background Cognitive impairment is a common and devastating manifestation in
Parkinson's disease (PD). We aimed to identify modifiable risk factors for PD with cognitive …

Progression in parkinson's disease: variation in motor and non‐motor symptoms severity and predictors of decline in cognition, motor function, disability, and health …

P Bugalho, F Ladeira, R Barbosa… - Movement Disorders …, 2021 - Wiley Online Library
Background Parkinson's disease (PD) is multi‐symptom disease with variable progression.
Objectives We performed a longitudinal study to address the evolution of motor symptoms …

Subjective Cognitive Complaints in Parkinson's Disease: A Systematic Review and Meta‐Analysis

M Siciliano, A Tessitore, F Morgante… - Movement …, 2024 - Wiley Online Library
Abstract Background Subjective cognitive complaints (SCCs) in Parkinson's disease (PD)
are reported frequently, but their prevalence and association with changes on objective …

Association of Baseline Depression and Anxiety with Longitudinal Health Outcomes in Parkinson's Disease

Y Shi, R Dobkin, D Weintraub, HR Cho… - Movement Disorders …, 2024 - Wiley Online Library
Background Anxiety and depression are common non‐motor symptoms in Parkinson's
disease (PD) but remain under‐recognized and under‐treated. Objectives To evaluate …

Impact of mild cognitive impairment on quality of life in young and typical onset Parkinson's disease

HM Holden, CN Schweer… - … disorders clinical practice, 2022 - Wiley Online Library
Introduction Younger age of onset and mild cognitive impairment (MCI) are both
independently associated with poorer quality of life (QOL) in Parkinson's disease (PD) …

Neuropsychiatric symptoms are associated with dementia in Parkinson's disease but not predictive of it

KL Horne, MR MacAskill, DJ Myall… - Movement Disorders …, 2021 - Wiley Online Library
ABSTRACT Background Neuropsychiatric symptoms in Parkinson's disease (PD) may
increase dementia (PDD) risk. The predictive value of these symptoms, however, has not …