Pulmonary arterial hypertension (PAH) is responsible for the premature death mainly
because of progressive and severe heart failure. This disease is characterized by increased …

Severe forms of pulmonary arterial hypertension (PAH) are characterized by various
degrees of remodeling of the pulmonary arterial vessels, which increases the pulmonary …

At present, six groups of chronic pulmonary hypertension (PH) are described. Among these,
group 1 (and 1′) comprises a group of diverse diseases termed pulmonary arterial …

Abstract World Health Organization category 1 pulmonary hypertension (PH) is a
heterogeneous syndrome in which PH originates in the small pulmonary arteries and is …

Therapeutic options for pulmonary arterial hypertension (PAH) have increased over the last
decades. The advent of pharmacological therapies targeting the prostacyclin, endothelin …

Pulmonary arterial hypertension (PAH) is a progressive pulmonary vasoproliferative
disorder characterized by the development of unique neointimal lesions, including …

Pulmonary arterial hypertension (PAH) is a unique disease. Properly speaking, it is not a
disease of the lung. It can be seen more as a microvascular disease occurring mainly in the …

Pulmonary arterial hypertension (PAH) is a serious pathological phenomenon with poor
prognosis, which is associated with morphological as well as hemodynamic alteration of the …

Pulmonary arterial hypertension (PAH) is a vascular remodeling disease with a relentless
course toward heart failure and early death. Existing PAH therapies, all of which were …

Rationale: The complex pathologies associated with severe pulmonary arterial hypertension
(PAH) in humans have been a challenge to reproduce in mice due to the subtle phenotype …