Control of the hypothalamo-pituitary-adrenal axis in the neonatal period: adrenocorticotropin and corticosterone stress responses dissociate in vasopressin-deficient …

D Zelena, A Domokos, I Barna, Z Mergl, J Haller… - …, 2008 - academic.oup.com
In adulthood the hypothalamo-pituitary-adrenal axis is controlled by both CRH and arginine
vasopressin (AVP). However, in neonates CRH secretion is very low, whereas AVP …

Congenital absence of vasopressin and age-dependent changes in ACTH and corticosterone stress responses in rats

D Zelena, I Barna, O Pinter, B Klausz, J Varga… - Stress, 2011 - Taylor & Francis
The hypothalamic components of the hypothalamo–pituitary–adrenal axis (HPA) are
corticotropin-releasing hormone (CRH) and vasopressin. To test the hypothesis that HPA …

Gender‐specific Regulation of the Hypothalamo‐pituitary‐adrenal axis and the Role of Vasopressin during the Neonatal Period

GB Makara, A Domokos, Z Mergl… - Annals of the New …, 2008 - Wiley Online Library
Studies in arginine vasopressin (AVP)‐deficient Brattleboro rats suggest that AVP is the
predominant secretagogue during the perinatal period. Here we tested the hypothesis that …

Reduced hypothalamic vasopressin secretion underlies attenuated adrenocorticotropin stress responses in pregnant rats

S Ma, MJ Shipston, D Morilak, JA Russell - Endocrinology, 2005 - academic.oup.com
We sought to explain decreased ACTH secretory responses to stress in pregnant rats by
investigating hypothalamic CRH and vasopressin secretion and actions on anterior pituitary …

Stress-induced alterations in corticotropin-releasing hormone and vasopressin gene expression in the paraventricular nucleus during ontogeny

GW Dent, DK Okimoto, MA Smith, S Levine - Neuroendocrinology, 2000 - karger.com
From postnatal day (PND) 4 to 14, neonates display a minimal pituitary-adrenal response to
mild stress, the so-called 'stress hyporesponsive period'(SHRP). During the SHRP, maternal …

[PDF][PDF] Blunted HPA axis response in lactating, vasopressin-deficient Brattleboro rats

A Fodor, O Pintér, A Domokos, K Langnaese… - J …, 2013 - researchgate.net
Adaptation to stress is a basic phenomenon in mammalian life that is mandatorily associated
with the activity of the hypothalamic–pituitary–adrenal (HPA) axis. An increased resting …

The vasopressin-deficient Brattleboro rat: lessons for the hypothalamo–pituitary–adrenal axis regulation

GB Makara, J Varga, I Barna, O Pintér, B Klausz… - Cellular and molecular …, 2012 - Springer
Adaptation to stress is indispensable to life and the hypothalamo–pituitary–adrenocortical
axis is one of the major components of the adaptation. The hypothalamic component …

Neonatal facilitation of stress-induced adrenocorticotropin secretion by prior stress: evidence for increased central drive to the pituitary

CD Walker, MF Dallman - Endocrinology, 1993 - academic.oup.com
The adrenocortical system of the neonatal rat exhibits both normal pituitary (ACTH) and
blunted adrenal corticosterone (B) responses to a variety of different stressors. It is …

Enhanced glucocorticoid feedback inhibition of hypothalamo-pituitary-adrenal responses to stress in adult rats neonatally treated with dexamethasone

PJGH Kamphuis, JM Bakker, MH Broekhoven… - …, 2002 - karger.com
We studied the long-term effect of neonatal treatment with the synthetic glucocorticoid
dexamethasone (DEX) on stress responsivity later in life. It was found that the plasma …

Maternal Genotype Influences Stress Reactivity of Vasopressin‐Deficient Brattleboro Rats

D Zelena, Z Mergl, GB Makara - Journal of neuroendocrinology, 2003 - Wiley Online Library
The role of vasopressin, cosecreted with corticotropin‐releasing hormone (CRH), in stress is
debated, because both normal as well as reduced adrenocorticotropin hormone (ACTH) rise …