A recent article [1] addresses the important issue of network-based metabolic pathway
analysis. Various methods have been used to define systemic pathways for metabolic …

Metabolic pathway analysis is becoming increasingly important for assessing inherent
network properties in (reconstructed) biochemical reaction networks. Of the two most …

Network-based definitions of biochemical pathways have emerged in recent years. These
pathway definitions insist on the balanced use of a whole network of biochemical reactions …

Motivation: The analysis of structure, pathways and flux distributions in metabolic networks
has become an important approach for understanding the functionality of metabolic systems …

Pathways are typically the central concept in the analysis of biochemical reaction networks.
A pathway can be interpreted as a chain of enzymatical reactions performing a specific …

The analysis of metabolic networks has become a major topic in biotechnology in recent
years. Applications range from the enhanced production of selected outputs to the prediction …

Important efforts are being done to systematically identify the relevant pathways in a
metabolic network. Unsurprisingly, there is not a unique set of network‐based pathways to …

Metabolic networks comprise a multitude of enzymatic reactions carrying out various
functions related to cell growth and product formation. Although such reactions are …

Motivation: A useful approach to unraveling and understanding complex biological networks
is to decompose networks into basic functional and structural units. Recent application of …

Metabolic network analysis based on stoichiometric and constraint-based methods has
become one of the most popular and successful modeling approaches in network and …