[18 F]-Group 13 fluoride derivatives as radiotracers for positron emission tomography

K Chansaenpak, B Vabre, FP Gabbaï - Chemical Society Reviews, 2016 - pubs.rsc.org
The field of 18F chemistry is rapidly expanding because of the use of this radionuclide in
radiotracers for positron emission tomography (PET). Until recently, most [18F]-radiotracers …

Inorganic approaches for radiolabelling biomolecules with fluorine-18 for imaging with positron emission tomography

GE Smith, HL Sladen, SCG Biagini, PJ Blower - Dalton Transactions, 2011 - pubs.rsc.org
Conventional methods for radiolabelling biomolecules such as proteins and peptides with
fluorine-18 for PET imaging rely on carbon–fluorine bond formation and are complex and …

[HTML][HTML] A Comprehensive Review of Non-Covalent Radiofluorination Approaches Using Aluminum [18F]fluoride: Will [18F]AlF Replace 68Ga for Metal Chelate …

C Fersing, A Bouhlel, C Cantelli, P Garrigue… - Molecules, 2019 - mdpi.com
Due to its ideal physical properties, fluorine-18 turns out to be a key radionuclide for positron
emission tomography (PET) imaging, for both preclinical and clinical applications. However …

Fluorine-18 radiochemistry, labeling strategies and synthetic routes

O Jacobson, DO Kiesewetter, X Chen - Bioconjugate chemistry, 2015 - ACS Publications
Fluorine-18 is the most frequently used radioisotope in positron emission tomography (PET)
radiopharmaceuticals in both clinical and preclinical research. Its physical and nuclear …

[18F] Fluoroalkyl agents: synthesis, reactivity and application for development of PET ligands in molecular imaging

MR Zhang, K Suzuki - Current Topics in Medicinal Chemistry, 2007 - ingentaconnect.com
Fluorine-18 (18F, β+; 96.7%, T1/2= 109.8 min) is of considerable importance for developing
positron emission tomography (PET) ligands for imaging receptor, enzyme, gene expression …

[18F]-Organotrifluoroborates as Radioprosthetic Groups for PET Imaging: From Design Principles to Preclinical Applications

DM Perrin - Accounts of Chemical Research, 2016 - ACS Publications
Conspectus Positron emission tomography (PET) is revolutionizing our ability to visualize in
vivo targets for target validation and personalized medicine. Of several classes of imaging …

[HTML][HTML] Closing the gap between 19F and 18F chemistry

J Ajenjo, G Destro, B Cornelissen… - EJNMMI Radiopharmacy …, 2021 - Springer
Positron emission tomography (PET) has become an invaluable tool for drug discovery and
diagnosis. The positron-emitting radionuclide fluorine-18 is frequently used in PET …

Fluorine‐18 chemistry for molecular imaging with positron emission tomography

F Dollé, D Roeda, B Kuhnast, MC Lasne - Fluorine and health, 2008 - Elsevier
Publisher Summary Positron emission tomography (PET) is a high-resolution, sensitive,
functional-imaging technique in nuclear medicine that permits repeated, non-invasive …

Derisking the Cu-Mediated 18F-Fluorination of Heterocyclic Positron Emission Tomography Radioligands

NJ Taylor, E Emer, S Preshlock… - Journal of the …, 2017 - ACS Publications
Molecules labeled with fluorine-18 (18F) are used in positron emission tomography to
visualize, characterize and measure biological processes in the body. Despite recent …

Radiochemistry with {Al18F} 2+: Current status and optimization perspectives for efficient radiofluorination by complexation

S Schmitt, E Moreau - Coordination Chemistry Reviews, 2023 - Elsevier
With the aim to efficiently develop and synthesize new radiotracers for PET imaging, and
their use for theranostic approaches, radiolabeling technics have not ceased to progress …