Antitumor activity of a unique polymer that incorporates a fluorescent self-assembled metallacycle
Despite the well-known anticancer activity of mono-and multinuclear platinum complexes,
studies of the antitumor performances of platinum-based supramolecular coordination …
studies of the antitumor performances of platinum-based supramolecular coordination …
Highly emissive self-assembled BODIPY-platinum supramolecular triangles
Light-emitting supramolecular coordination complexes (SCCs) have been widely studied for
applications in the chemical and biological sciences. Herein, we report the coordination …
applications in the chemical and biological sciences. Herein, we report the coordination …
Polymeric nanoparticles integrated from discrete organoplatinum (II) metallacycle by stepwise post-assembly polymerization for synergistic cancer therapy
Post-assembly modification is a useful tool for producing discrete metallasupramolecular
structures. However, the simple structural transformation by facile covalent reactions greatly …
structures. However, the simple structural transformation by facile covalent reactions greatly …
β-Cyclodextrin modified Pt (II) metallacycle-based supramolecular hyperbranched polymer assemblies for DOX delivery to liver cancer cells
W Chen, X Li, C Liu, J He, M Qi, Y Sun… - Proceedings of the …, 2020 - National Acad Sciences
Despite the widespread clinical application of chemotherapeutic anticancer drugs, their
adverse side effects and inefficient performances remain ongoing issues. A drug delivery …
adverse side effects and inefficient performances remain ongoing issues. A drug delivery …
Tetraphenylethene-based highly emissive metallacage as a component of theranostic supramolecular nanoparticles
A theranostic agent combines diagnostic reporter with therapeutic activity in a single entity,
an approach that seeks to increase the efficacy of cancer treatment. Herein, we describe the …
an approach that seeks to increase the efficacy of cancer treatment. Herein, we describe the …
Designed conformation and fluorescence properties of self-assembled phenazine-cored platinum (II) metallacycles
A series of platinum (II) metallacycles were prepared via the coordination-driven self-
assembly of a phenazine-cored dipyridyl donor with a 90° Pt (II) acceptor and various …
assembly of a phenazine-cored dipyridyl donor with a 90° Pt (II) acceptor and various …
Fluorescent metallacycle-cored polymers via covalent linkage and their use as contrast agents for cell imaging
The covalent linkage of supramolecular monomers provides a powerful strategy for
constructing dynamic polymeric materials whose properties can be readily tuned either by …
constructing dynamic polymeric materials whose properties can be readily tuned either by …
Coordination polymer particles as potential drug delivery systems
I Imaz, M Rubio-Martínez, L García-Fernández… - Chemical …, 2010 - pubs.rsc.org
Micro-and nanoscale coordination polymer particles can be used for encapsulating and
delivering drugs. In vitro cancer cell cytotoxicity assays showed that these capsules readily …
delivering drugs. In vitro cancer cell cytotoxicity assays showed that these capsules readily …
Bioactive polymeric metallosomes self-assembled through block copolymer–metal complexation
Spontaneous formation of polymeric metallosomes with uniform size (∼ 100 nm) was found
to occur in aqueous medium through the reaction of an anticancer agent,(1, 2 …
to occur in aqueous medium through the reaction of an anticancer agent,(1, 2 …
Cyclic peptide–polymer nanotubes as efficient and highly potent drug delivery systems for organometallic anticancer complexes
Functional drug carrier systems have potential for increasing solubility and potency of drugs
while reducing side effects. Complex polymeric materials, particularly anisotropic structures …
while reducing side effects. Complex polymeric materials, particularly anisotropic structures …