Supramolecular nanoassembly of lysozyme and α-lactalbumin (apo α-LA) exhibits selective cytotoxicity and enhanced bioavailability of curcumin to cancer cells
Hybrid supramolecular spherical nanoassembly of hen egg white lysozyme and bovine apo
α lactalbumin (SN LYZ-BLA) was prepared with a mean size of˜ 55.2 nm using an optimized …
α lactalbumin (SN LYZ-BLA) was prepared with a mean size of˜ 55.2 nm using an optimized …
Surface conjugation of curcumin with self-assembled lysozyme nanoparticle enhanced its bioavailability and therapeutic efficacy in multiple cancer cells
Here, we prepared nano self-assembly of lysozyme via a directed optimized desolvation
process and conjugated it with an anticancer natural polyphenol, curcumin (Cur) onto the …
process and conjugated it with an anticancer natural polyphenol, curcumin (Cur) onto the …
An α-tocopheryl succinate enzyme-based nanoassembly for cancer imaging and therapy
SY Lee, HJ Cho - Drug Delivery, 2018 - Taylor & Francis
Nanoassembly (NA) based on a D-α-tocopherol succinate (αTS) conjugated lysozyme
(Lys)(Lys-αTS) was fabricated for tumor-selective delivery of curcumin (CUR) for breast …
(Lys)(Lys-αTS) was fabricated for tumor-selective delivery of curcumin (CUR) for breast …
Synergistically enhanced anticancer effect of codelivered curcumin and siPlk1 by stimuli-responsive α-lactalbumin nanospheres
D Li, M Shi, C Bao, W Bao, L Zhang, L Jiao, T Li… - Nanomedicine, 2019 - Taylor & Francis
Aim: To achieve enhanced anticancer efficacy by combined siPlk1 and curcumin (cur)
therapy using α-lactalbumin (α-lac) nanocarrier delivery. Materials & methods: α-Lac was …
therapy using α-lactalbumin (α-lac) nanocarrier delivery. Materials & methods: α-Lac was …
Stable self-assembly of bovine α-lactalbumin exhibits target-specific antiproliferative activity in multiple cancer cells
Self-assembly of a protein is a natural phenomenon; however, the process can be
performed under a suitable condition in vitro. Since proteins are nontoxic, biodegradable …
performed under a suitable condition in vitro. Since proteins are nontoxic, biodegradable …
Bio-conjugation of curcumin with self-assembled casein nanostructure via surface loading enhances its bioactivity: an efficient therapeutic system
In this study, self-assembled nanostructure of casein (NS CS) of spherical shape was
prepared using an optimized desolvation method with a mean size of 45 nm. Curcumin …
prepared using an optimized desolvation method with a mean size of 45 nm. Curcumin …
[HTML][HTML] Solubilization and protection of curcumin based on lysozyme/albumin nano-complex
W Xu, P Ge, L Huang, Z Du, X Liu, J Li, N Yang - Aip Advances, 2018 - pubs.aip.org
Curcumin (Cur) has the function of anti-inflammatory, antioxidant and other pharmacological
effects. To further improve its solubility and stability, egg albumin/lysozyme (Alb/Ly) nano …
effects. To further improve its solubility and stability, egg albumin/lysozyme (Alb/Ly) nano …
Stable self-assembled nanostructured hen egg white lysozyme exhibits strong anti-proliferative activity against breast cancer cells
Chemotherapy side effects have long been a matter of great concern. Here we describe a
structurally stable self-assembled nanostructured lysozyme (snLYZ) synthesized using a …
structurally stable self-assembled nanostructured lysozyme (snLYZ) synthesized using a …
Celecoxib-induced self-assembly of smart albumin-doxorubicin conjugate for enhanced cancer therapy
L Shi, L Xu, C Wu, B Xue, X Jin, J Yang… - ACS applied materials & …, 2018 - ACS Publications
Recent years have witnessed the great contributions that drug combination therapy has
made for enhanced cancer therapy. However, because of the complicated pharmacokinetics …
made for enhanced cancer therapy. However, because of the complicated pharmacokinetics …
Co-assembly of curcumin and a cystine bridged peptide to construct tumor-responsive nano-micelles for efficient chemotherapy
Y Dai, Z Jiang, J Li, M Wang, C Liu, W Qi… - Journal of materials …, 2020 - pubs.rsc.org
The effective uptake and release of hydrophobic antitumor drugs in cancer cells is a
practical challenge for tumor chemotherapy. Many methods were developed to conquer it …
practical challenge for tumor chemotherapy. Many methods were developed to conquer it …
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