Co-encapsulation of curcumin and doxorubicin in albumin nanoparticles blocks the adaptive treatment tolerance of cancer cells

SM Motevalli, AS Eltahan, L Liu, A Magrini, N Rosato… - Biophysics Reports, 2019 - Springer
The adaptive treatment tolerance (ATT) of cancer cells is the main encumbrance to cancer
chemotherapy. A potential solution to this problem is to treat cancer cells with multiple drugs …

Synthesis, characterization, in-silico and in-vitro anticancer studies of Plumbagin encapsulated albumin nanoparticles for breast cancer treatment

R Solanki, M Saini, J Mochi, A Pappachan… - Journal of Drug Delivery …, 2023 - Elsevier
Abstract Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone) is a naturally occurring
phytochemical, mainly found in the roots of the Plumbago zeylanica L. Plumbagin (PLB) …

Self-assembled nanoplatform for targeted delivery of chemotherapy agents via affinity-regulated molecular interactions

S Park, S Kang, AJ Veach, Y Vedvyas, R Zarnegar… - Biomaterials, 2010 - Elsevier
Site-specific delivery of drugs while minimizing unwanted distribution has been one of the
pursued goals in cancer therapy. In this endeavor, we have developed targeted polymeric …

Self-assembled biodegradable protein–polymer vesicle as a tumor-targeted nanocarrier

Z Liu, C Dong, X Wang, H Wang, W Li… - … applied materials & …, 2014 - ACS Publications
Self-assembled nanostructures based on amphiphilic protein–polymer conjugates have
shown great advantages in the field of nanomedicine such as inherent biocompatibility with …

Intercalation of curcumin into liposomal chemotherapeutic agent augments apoptosis in breast cancer cells

R Mahmoudi, F Hassandokht… - Journal of …, 2021 - journals.sagepub.com
Resistance to common chemotherapeutic agents is a frequent phenomenon in late-stage
breast cancers. An ideal system capable of the co-delivery of hydrophobic and hydrophilic …

Supramolecular Structures Generated via Self-Assembly of a Cell Penetrating Tetrapeptide Facilitate Intracellular Delivery of a Pro-apoptotic Chemotherapeutic Drug

S Sivagnanam, M Basak, A Kumar, K Das… - ACS Applied Bio …, 2021 - ACS Publications
Development of drug carriers, which can chaperone xenobiotics directly to their site of
action, is an essential step for the advancement of precision medicine. Cationic …

Albumin biomimetic nanocorona improves tumor targeting and penetration for synergistic therapy of metastatic breast cancer

H Cao, L Zou, B He, L Zeng, Y Huang… - Advanced Functional …, 2017 - Wiley Online Library
The synergistic combination of photothermal and RNA interference therapy demonstrates
great potential for effective treatment of metastatic breast cancer, but their efficacy is limited …

Fabrication and characterization of biocompatible hybrid nanoparticles from spontaneous co-assembly of casein/gliadin and proanthocyanidin

C Liu, M Li, J Yang, L Xiong, Q Sun - Food Hydrocolloids, 2017 - Elsevier
Proanthocyanidins (PACs), a group of polyphenolic secondary metabolites in plants, have
drawn great interest because of their enormous potential in reducing the incidence of …

Designing biocompatible protein nanoparticles for improving the cellular uptake and antioxidation activity of tetrahydrocurcumin

S Chen, Q Wu, M Ma, Z Huang, F Vriesekoop… - Journal of Drug Delivery …, 2021 - Elsevier
Tetrahydrocurcumin (THC) is a natural molecule with anticancerous, antioxidant and other
beneficial activities. However, its low aqueous solubility leads to poor bioavailability. Sodium …

Self-assembled drug loaded glycosyl-protein metal nanoconstruct: detailed synthetic procedure and therapeutic effect in solid tumor treatment

BS Unnikrishnan, S Maya, GU Preethi… - Colloids and Surfaces B …, 2020 - Elsevier
Nanotechnology-based drug delivery research has largely focused on developing well
efficient localized delivery therapeutic agents to overcome the limitations of non-specificity …