Elevated free fatty acids affect bovine granulosa cell function: a molecular cue for compromised reproduction during negative energy balance

A Sharma, VS Baddela, F Becker… - Endocrine …, 2019 - ec.bioscientifica.com
High-yielding dairy cows postpartum face the challenge of negative energy balance leading
to elevated free fatty acids levels in the serum and follicular fluid thus affecting the ovarian …

Effect of non-esterified fatty acids on bovine granulosa cell steroidogenesis and proliferation in vitro

T Vanholder, J Leroy, A Van Soom, G Opsomer… - Animal reproduction …, 2005 - Elsevier
In high-yielding dairy cows, the negative energy balance (NEB) during the first weeks post
partum may influence dominant follicle growth and steroidogenesis. Since non-esterified …

Polyunsaturated fatty acids in male and female reproduction

DC Wathes, DRE Abayasekara… - Biology of …, 2007 - academic.oup.com
In Westernized societies, average consumption of n-6 polyunsaturated fatty acids (PUFAs)
far exceeds nutritional requirements. The ratio of n-6 to n-3 PUFAs is generally> 10: 1 …

Sex determination in mammalian germ cells: extrinsic versus intrinsic factors

J Bowles, P Koopman - Reproduction, 2010 - rep.bioscientifica.com
Diets or supplements high in n-3 and n-6 polyunsaturated fatty acids (PUFAs) have been
shown to influence the timing of parturition. PUFAs are substrates for prostaglandin (PG) …

Ingestion of n-3 polyunsaturated fatty acids and ovulation in rats

EP Trujillo, KS Broughton - Reproduction, 1995 - rep.bioscientifica.com
The effects of different ratios of dietary (n-3):(n-6) polyunsaturated fatty acids on
prostaglandin E, prostaglandin F 2α and ovulation in rats were assessed. Dietary (n-3) …

Bovine cumulus cells protect maturing oocytes from increased fatty acid levels by massive intracellular lipid storage

H Aardema, F Lolicato, CHA van de Lest… - Biology of …, 2013 - academic.oup.com
Metabolic conditions characterized by elevated free fatty acid concentrations in blood and
follicular fluid are often associated with impaired female fertility. Especially elevated …

Effect of level of dietary n-3 polyunsaturated fatty acid supplementation on systemic and tissue fatty acid concentrations and on selected reproductive variables in …

S Childs, AA Hennessy, JM Sreenan, DC Wathes… - Theriogenology, 2008 - Elsevier
Reproductively normal crossbred beef heifers were individually offered a diet of barley straw
and concentrate supplemented with one of four levels of a fish oil (FO) enriched supplement …

Metabolite concentrations in follicular fluid may explain differences in fertility between heifers and lactating cows

K Bender, S Walsh, ACO Evans, T Fair… - …, 2010 - rep.bioscientifica.com
There has been a marked decline in the fertility of dairy cows over the past decades, and
metabolomic analysis offers a potential to investigate the underlying causes. Metabolite …

[PDF][PDF] Effects of dietary polyunsaturated fatty acids on ovarian function and prostaglandin secretion in lactating dairy cows

H Ghasemzadeh-Nava, F Fatahnia, A Nikkhah… - International Journal of …, 2011 - sid.ir
As lactating cows in severe negative energy balance have poor reproductive performance,
the effect of dietary fat supplementation (fish oil, soybean oil) on PGFM secretion, ovarian …

Non‐esterified fatty acid‐associated ability of follicular fluid to support porcine oocyte maturation and development

K Ogawa, N Itami, M Ueda, K Kansaku… - Reproductive …, 2018 - Wiley Online Library
Purpose The effect of supplementing maturation medium with follicular fluid (FF) was
examined according to its non‐esterified fatty acid (NEFA) content or with a fatty acid mixture …