Peripheral immune signatures in Alzheimer disease
D Goldeck, JM Witkowski, T Fülop… - Current Alzheimer …, 2016 - ingentaconnect.com
According to the current paradigm, the main cause of AD is the accumulation of neurotoxic
amyloid beta (Aβ) peptide aggregates resulting from the cleavage of the amyloid precursor …
amyloid beta (Aβ) peptide aggregates resulting from the cleavage of the amyloid precursor …
Peripheral immune system in aging and Alzheimer's disease
W Cao, H Zheng - Molecular neurodegeneration, 2018 - Springer
Alzheimer's disease (AD) represents an urgent public health mandate. AD is no longer
considered a neural-centric disease; rather, a plethora of recent studies strongly implicate a …
considered a neural-centric disease; rather, a plethora of recent studies strongly implicate a …
Neuroinflammation, immune system and Alzheimer disease: searching for the missing link
F Guerriero, C Sgarlata, M Francis, N Maurizi… - Aging clinical and …, 2017 - Springer
Due to an increasingly aging population, Alzheimer disease (AD) represents a crucial issue
for the healthcare system because of its widespread prevalence and the burden of its care …
for the healthcare system because of its widespread prevalence and the burden of its care …
Immune modulations and immunotherapies for Alzheimer's disease: a comprehensive review
Abstract Alzheimer's disease (AD), the most common cause of dementia, is characterized by
progressive cognitive and memory impairment ensued from neuronal dysfunction and …
progressive cognitive and memory impairment ensued from neuronal dysfunction and …
The impact of ageing on the CNS immune response in Alzheimer's disease
SEJ Chee, E Solito - Frontiers in Immunology, 2021 - frontiersin.org
Alzheimer's Disease (AD) is a progressive neurodegenerative disease strongly associated
with increasing age. Neuroinflammation and the accumulation of amyloid protein are …
with increasing age. Neuroinflammation and the accumulation of amyloid protein are …
Potential immunotargets for Alzheimer's disease treatment strategies
PL Fernández, GB Britton… - Journal of Alzheimer's …, 2013 - content.iospress.com
Alzheimer's disease (AD) exerts a profound burden on public health worldwide. AD etiology
is unknown, and research to understand its underlying pathology has produced agents for …
is unknown, and research to understand its underlying pathology has produced agents for …
Innate immune system and inflammation in Alzheimer's disease: from pathogenesis to treatment
M Serpente, R Bonsi, E Scarpini… - Neuroimmunomodulation, 2014 - karger.com
Immune activation and inflammation, likely triggered by amyloid-beta (Aβ) deposition, play a
remarkable role in the pathogenesis of Alzheimer's disease (AD), which is the most frequent …
remarkable role in the pathogenesis of Alzheimer's disease (AD), which is the most frequent …
Neuroinflammation in Alzheimer's disease: friend or foe?
C Scuderi, R Facchinetti, L Steardo… - The FASEB …, 2020 - Wiley Online Library
Neuroinflammation is part of the complex immune response within the central nervous
system (CNS), whose details have been partially elucidated. The CNS immune response …
system (CNS), whose details have been partially elucidated. The CNS immune response …
Neuroinflammation in Alzheimer's disease: from pathogenesis to a therapeutic target
SW Pimplikar - Journal of clinical immunology, 2014 - Springer
The top-down, reductionist approach of the past three decades has resulted in remarkable
progress in identifying genes and proteins involved in Alzheimer's disease (AD), including β …
progress in identifying genes and proteins involved in Alzheimer's disease (AD), including β …
Role of the peripheral innate immune system in the development of Alzheimer's disease
Alzheimer's disease is one of the most devastating neurodegenerative diseases. The exact
cause of the disease is still not known although many scientists believe in the beta amyloid …
cause of the disease is still not known although many scientists believe in the beta amyloid …