The growing understanding of the biology of disorders of consciousness has led to a
renaissance in the development of therapeutic interventions for patients with disorders of …

The concept of consciousness continues to defy definition and elude the grasp of
philosophical and scientific efforts to formulate a testable construct that maps to human …

Major advances have been made over the past few decades in identifying and managing
disorders of consciousness (DOC) in patients with acquired brain injury (ABI), bringing the …

Without controlled studies and careful patient selection criteria it will not be possible to
evaluate the potential of therapeutic interventions in disorders of consciousness. There also …

The management of patients with severe brain injuries and prolonged disorders of
consciousness raises important issues particularly with respect to their therapeutic options …

Abstract Background/Objective For patients with disorders of consciousness (DoC) and their
families, the search for new therapies has been a source of hope and frustration. Almost all …

Objective To update the 1995 American Academy of Neurology (AAN) practice parameter on
persistent vegetative state and the 2002 case definition for the minimally conscious state …

Objective What mechanisms underlie the loss and recovery of consciousness after severe
brain injury? We sought to establish, in the largest cohort of patients with disorders of …

Pharmacologic interventions are commonly used to support rehabilitation efforts of patients
with disorders of consciousness (DoC). The 2018 practice guidelines recommend …

The last years have witnessed a significant increase in our understanding of brain functions
in survivors of severe brain injuries with disorders of consciousness (DOC). Despite there is …