Optimizing boron neutron capture therapy (BNCT) to treat cancer: an updated review on the latest developments on boron compounds and strategies

A Monti Hughes, N Hu - Cancers, 2023 - mdpi.com
Simple Summary Boron neutron capture therapy (BNCT) is a tumor-selective particle
radiotherapy. It combines preferential boron accumulation in tumors and neutron irradiation …

Importance of radiobiological studies for the advancement of boron neutron capture therapy (BNCT)

AM Hughes - Expert Reviews in Molecular Medicine, 2022 - cambridge.org
Boron neutron capture therapy (BNCT) is a tumour selective particle radiotherapy, based on
the administration of boron carriers incorporated preferentially by tumour cells, followed by …

Boron neutron capture therapy: Moving toward targeted cancer therapy

HR Mirzaei, A Sahebkar, R Salehi… - Journal of cancer …, 2016 - journals.lww.com
Boron neutron capture therapy (BNCT) occurs when a stable isotope, boton-10, is irradiated
with low-energy thermal neutrons to yield stripped down helium-4 nuclei and lithium-7 …

Boron neutron capture therapy: a review of clinical applications

TD Malouff, DS Seneviratne, DK Ebner… - Frontiers in …, 2021 - frontiersin.org
Boron neutron capture therapy (BNCT) is an emerging treatment modality aimed at
improving the therapeutic ratio for traditionally difficult to treat tumors. BNCT utilizes …

Boron neutron capture therapy at the crossroads-Where do we go from here?

RF Barth, JC Grecula - Applied Radiation and Isotopes, 2020 - Elsevier
As elegant as is the concept upon which Boron Neutron Capture Therapy (BNCT) is based,
unfortunately it has not gained widespread acceptance by the physicians who are treating …

The dawn of a new era: tumor-targeting boron agents for neutron capture therapy

T Luo, W Huang, F Chu, T Zhu, B Feng… - Molecular …, 2023 - ACS Publications
Cancer is widely recognized as one of the most devastating diseases, necessitating the
development of intelligent diagnostic techniques, targeted treatments, and early prognosis …

Next generation of boron neutron capture therapy (BNCT) agents for cancer treatment

P Coghi, J Li, NS Hosmane… - Medicinal Research …, 2023 - Wiley Online Library
Boron neutron capture therapy (BNCT) is one of the most promising treatments among
neutron capture therapies due to its long‐term clinical application and unequivocally …

Boron neutron capture therapy: Current status and challenges

S Wang, Z Zhang, L Miao, Y Li - Frontiers in Oncology, 2022 - frontiersin.org
Boron neutron capture therapy (BNCT) is a re-emerging therapy with the ability to selectively
kill tumor cells. After the boron delivery agents enter the tumor tissue and enrich the tumor …

Boron neutron capture therapy (BNCT): A radiation oncology perspective

RV Dorn - International Journal of Radiation Oncology* Biology …, 1994 - Elsevier
Boron neutron capture therapy (BNCT) offers considerable promise in the search for the
ideal cancer therapy, a therapy which selectively and maximally damages malignant cells …

Multi-functional boron-delivery agents for boron neutron capture therapy of cancers

SO Oloo, KM Smith, MGH Vicente - Cancers, 2023 - mdpi.com
Simple Summary Many boron-containing compounds have been synthesized and proposed
as boron-delivery agents for boron neutron capture therapy for cancers, including brain …