The importance of T‐cell receptor (TCR) repertoire diversity is highlighted in murine models
of immunodeficiency and in many human pathologies. However, the true extent of TCR …

In this study we characterized the TCR repertoire profiles in patients with chronic
progressive inflammatory neurological disorders including HAM/TSP, associated with …

T cells are an integral component of the adaptive immune response via the recognition of
peptides by the cell surface-expressed T cell receptor (TCR). Rearrangement of the TCR …

Objective To characterize T‐cell receptors (TCRs) and identify target epitopes in multiple
sclerosis (MS). Methods Peripheral blood mononuclear cells were obtained from 39 MS …

Activated T cells play a central role in autoimmune disease. Evidence from animal models,
such as experimental allergic encephalitis, has shown that pathogenic T cells use a …

Multiple sclerosis is an inflammatory demyelinating disease of the CNS associated with T
cells autoreactive for myelin components. In this study, we analysed the T‐cell receptor …

Epstein‐Barr virus (EBV) has long been suggested as a pathogen in multiple sclerosis (MS).
Here, we used high‐throughput sequencing to determine the diversity …

The ex vivo analysis of the T-cell receptor V-beta (TCRBV) gene usage by circulating T
lymphocytes in Multiple Sclerosis (MS) patients may contribute to understanding disease …

The T-cell receptor (TCR) is a highly polymorphic surface receptor that allows T-cells to
recognize antigenic peptides presented on the major histocompatibility complex (MHC) …

T cells recognizing self or microbial antigens may trigger or reactivate immune‐mediated
diseases. Monitoring the frequency of specific T cell clonotypes to assess a possible link …