Targeted Conservative Cointegrate Formation Mediated by IS26 Family Members Requires Sequence Identity at the Reacting End
ABSTRACT IS 26 forms cointegrates using two distinct routes, a copy-in mechanism
involving one insertion sequence (IS) and a target and a targeted conservative mechanism …
involving one insertion sequence (IS) and a target and a targeted conservative mechanism …
IS26 Family Members IS257 and IS1216 Also Form Cointegrates by Copy-In and Targeted Conservative Routes
ABSTRACT IS 26 has been shown to form cointegrates both by a copy-in mechanism
involving one insertion sequence (IS) and a target and by a targeted conservative …
involving one insertion sequence (IS) and a target and by a targeted conservative …
Movement of IS 26-associated antibiotic resistance genes occurs via a translocatable unit that includes a single IS 26 and preferentially inserts adjacent to another IS …
The insertion sequence IS 26 plays a key role in disseminating antibiotic resistance genes in
Gram-negative bacteria, forming regions containing more than one antibiotic resistance …
Gram-negative bacteria, forming regions containing more than one antibiotic resistance …
Transposase and cointegrase: specialized transposition proteins of the bacterial insertion sequence IS21 and related elements
B Berger, D Haas - Cellular and Molecular Life Sciences CMLS, 2001 - Springer
The bacterial insertion sequence IS 21 shares with many insertion sequences a two-step,
reactive junction transposition pathway, for which a model is presented in this review: a …
reactive junction transposition pathway, for which a model is presented in this review: a …
[HTML][HTML] The dynamic network of IS30 transposition pathways
F Olasz, M Szabó, A Veress, M Bibó, J Kiss - Plos one, 2022 - journals.plos.org
The E. coli element IS 30 has adopted the copy-out-paste-in transposition mechanism that is
prevalent in a number of IS-families. As an initial step, IS 30 forms free circular transposition …
prevalent in a number of IS-families. As an initial step, IS 30 forms free circular transposition …
IS26 and the IS26 family: versatile resistance gene movers and genome reorganizers
In Gram-negative bacteria, the insertion sequence IS 26 is highly active in disseminating
antibiotic resistance genes. IS 26 can recruit a gene or group of genes into the mobile gene …
antibiotic resistance genes. IS 26 can recruit a gene or group of genes into the mobile gene …
Targeted conservative formation of cointegrates between two DNA molecules containing IS26 occurs via strand exchange at either IS end
We recently proposed a model for targeted, conservative cointegrate formation between
DNA molecules each containing a copy of IS26, that involves Tnp26‐catalyzed strand …
DNA molecules each containing a copy of IS26, that involves Tnp26‐catalyzed strand …
[HTML][HTML] The IS6 family, a clinically important group of insertion sequences including IS26
The IS 6 family of bacterial and archaeal insertion sequences, first identified in the early
1980s, has proved to be instrumental in the rearrangement and spread of multiple antibiotic …
1980s, has proved to be instrumental in the rearrangement and spread of multiple antibiotic …
Cointegrase, a naturally occurring, truncated form of IS21 transposase, catalyzes replicon fusion rather than simple insertion of IS21
S Schmid, T Seitz, D Haas - Journal of molecular biology, 1998 - Elsevier
The bacterial insertion sequence IS21 contains two genes, istA and istB, which are
organized as an operon. IS21 spontaneously forms tandem repeats designated (IS21) 2 …
organized as an operon. IS21 spontaneously forms tandem repeats designated (IS21) 2 …
[HTML][HTML] Characterization of the specific DNA-binding properties of Tnp26, the transposase of insertion sequence IS26
The bacterial insertion sequence (IS) IS26 mobilizes and disseminates antibiotic resistance
genes. It differs from bacterial IS that have been studied to date as it exclusively forms …
genes. It differs from bacterial IS that have been studied to date as it exclusively forms …