The antihypertensive effects of treatment with a diuretic or a beta-blocker were compared in
40 patients with essential hypertension. Patients were allocated at random to receive one …

Patients with mild to moderate essential hypertension were treated with beta-blockers and
diuretics given separately and in combination. During single-drug therapy, the majority of …

Acebutolol, a new cardloselective beta-blocking agent, was administered for 48 hours to 44
patients with essential hypertension at a total dosage of 2.0 g (2,000 mg). The slowing down …

In this study, the relation between renin activity and therapeutic response to
hydrochlorothiazide or propranolol was studied. Patients with a diastolie blood pressure of …

The combination of hydrochlorothiazide (50 mg daily) and metoprolol (100 to 400 mg daily)
reduced erect systolic blood pressure by 23.8±4.0 (SE) mm Hg and erect diastolic pressure …

Fifty-five patients with mild to moderate, renal or essential hypertension were admitted to a
double blind cross-over trial of 18 weeks, involving treatment periods with placebo, the …

The antihypertensive efficacy and side effects of the combined therapy with propranolol,
phenoxybenzamine, and hydrochlorothiazide were examined in 17 patients with moderate …

The antihypertensive effect of intravenous (acute) and oral (long-term) beta-adrenergic
blockade with propranolol or pindolol was evaluated in 46 male patients with either …

The treatment response to beta-adrenoceptor blocking drugs was compared in two groups
of patients with primary (essential) hypertension and different renin levels. Each group …

The object of this study was to establish whether cardioselectivity of atenolol confers any
advantage over noncardioselective β‐blockade in the treatment of hypertension. A dose of …