[HTML][HTML] Progressive morphological changes and impaired retinal function associated with temporal regulation of gene expression after retinal ischemia/reperfusion …

BJ Kim, TA Braun, RJ Wordinger, AF Clark - Molecular neurodegeneration, 2013 - Springer
Retinal ischemia/reperfusion (I/R) injury is an important cause of visual impairment.
However, questions remain on the overall I/R mechanisms responsible for progressive …

[HTML][HTML] From ganglion cell to photoreceptor layer: timeline of deterioration in a rat ischemia/reperfusion model

M Palmhof, V Frank, P Rappard… - Frontiers in cellular …, 2019 - frontiersin.org
Neuronal damage and impaired vision in different retinal disorders are induced, among
other factors, by ischemia/reperfusion (I/R). Since the mechanisms and the progression of …

Time-dependent gene profiling indicates the presence of different phases for ischemia/reperfusion injury in retina

K Andreeva, M Zhang, W Fan, X Li… - … and eye diseases, 2014 - journals.sagepub.com
Ischemia/reperfusion (IR) injury has been associated with several retinal pathologies, and a
few genes/gene products have been linked to IR injury. However, the big picture of temporal …

[HTML][HTML] Differential temporal and spatial expression of immediate early genes in retinal neurons after ischemia–reperfusion injury

N Yoshimura, T Kikuchi, S Kuroiwa… - … ophthalmology & visual …, 2003 - arvojournals.org
purpose. To investigate genes that are up-and downregulated in rat retinal ischemia–
reperfusion injury systematically by using an oligonucleotide microarray system and to …

[HTML][HTML] Optic nerve degeneration after retinal ischemia/reperfusion in a rodent model

M Renner, G Stute, M Alzureiqi, J Reinhard… - Frontiers in cellular …, 2017 - frontiersin.org
Retinal ischemia is a common pathomechanism in many ocular disorders such as age-
related macular degeneration (AMD), diabetic retinopathy, glaucoma or retinal vascular …

A mouse model of retinal ischemia-reperfusion injury through elevation of intraocular pressure

MJ Hartsock, H Cho, L Wu, WJ Chen, J Gong… - JoVE (Journal of …, 2016 - jove.com
Retinal ischemia-reperfusion (I/R) is a pathophysiological process contributing to cellular
damage in multiple ocular conditions, including glaucoma, diabetic retinopathy, and retinal …

[HTML][HTML] Mitogen-activated protein kinases in the porcine retinal arteries and neuroretina following retinal ischemia-reperfusion

B Gesslein, G Håkansson, R Carpio… - Molecular …, 2010 - ncbi.nlm.nih.gov
Purpose The aim of the present study was to examine changes in the expression of
intracellular signal-transduction pathways, specifically mitogen-activated protein kinases …

Dysregulation of neurotrophic and inflammatory systems accompanied by decreased CREB signaling in ischemic rat retina

XJ Guo, XS Tian, Z Ruan, YT Chen, L Wu… - Experimental eye …, 2014 - Elsevier
Although permanent bilateral common carotid artery occlusion (2VO) has been
demonstrated to induce retinal injury, there is still a lack of systematic research on the …

[HTML][HTML] A mouse model of retinal hypoperfusion injury induced by unilateral common carotid artery occlusion

D Lee, H Kang, KY Yoon, YY Chang, HB Song - Experimental eye research, 2020 - Elsevier
Retina, one of the highest oxygen demanding tissues, is vulnerable to vascular
insufficiencies, and various ocular vascular disorders can cause chronic retinal ischemia. To …

[HTML][HTML] Short-time ocular ischemia induces vascular endothelial dysfunction and ganglion cell loss in the pig retina

JK Zadeh, A Garcia-Bardon, EK Hartmann… - International Journal of …, 2019 - mdpi.com
Visual impairment and blindness are often caused by retinal ischemia-reperfusion (I/R)
injury. We aimed to characterize a new model of I/R in pigs, in which the intraocular …