[HTML][HTML] PDE4B induces epithelial-to-mesenchymal transition in bladder cancer cells and is transcriptionally suppressed by CBX7

Z Huang, J Liu, J Yang, Y Yan, C Yang, X He… - Frontiers in Cell and …, 2021 - frontiersin.org
Urinary bladder cancer (UBC) is a common malignant tumor with high incidence. Advances
in the diagnosis and treatment of this disease demand the identification of novel therapeutic …

[HTML][HTML] DEPDC1B is a tumor promotor in development of bladder cancer through targeting SHC1

CH Lai, K Xu, J Zhou, M Wang, W Zhang, X Liu… - Cell death & …, 2020 - nature.com
Bladder cancer is one of the most commonly diagnosed malignant tumors in the urinary
system and causes a massive cancer-related death. DEPDC1B is a DEP domain-containing …

[HTML][HTML] Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway

Y Du, Y Xu, X Guo, C Tan, X Zhu, G Liu, X Lyu, C Bei - BMC cancer, 2024 - Springer
Background Hepatocellular carcinoma (HCC) has a high mortality rate, and the mechanisms
underlying tumor development and progression remain unclear. However, inactivated tumor …

[HTML][HTML] PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway

H Gao, B Sun, H Fu, X Chi, F Wang, X Qi, J Hu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Protein disulfide isomerase family 6 (PDIA6) belongs to the protein disulfide isomerase (PDI)
family, which function as isomerases and molecular chaperones. PDIA6 has recently been …

[HTML][HTML] DPP4/CD26 overexpression in urothelial carcinoma confers an independent prognostic impact and correlates with intrinsic biological aggressiveness

PI Liang, BW Yeh, WM Li, TC Chan, IW Chang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Urothelial carcinoma (UC) is common cancer worldwide. The molecular aberrations
regarding tumor progression remain unclear. Pericellular proteolysis is crucial in …

[HTML][HTML] DDX11-AS1exacerbates bladder cancer progression by enhancing CDK6 expression via suppressing miR-499b-5p

Q Li, S Wang, Z Wu, Y Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Abstract Purpose We investigated DDX11-AS1 effects on bladder cancer (BLCA)
progression to identify a new potential therapeutic target for BLCA. Methods BLCA cases (n …

[HTML][HTML] The inhibitory effect of PDIA6 downregulation on bladder cancer cell proliferation and invasion

HP Cheng, Q Liu, Y Li, XD Li, CY Zhu - Oncology research, 2017 - ncbi.nlm.nih.gov
Protein disulfide isomerases A6 (PDIA6) belongs to the PDI family. Recently, PDIA6 was
found to have a close association with various cancers. However, there has been little …

DMBT1 suppresses progression of gallbladder carcinoma through PI3K/AKT signaling pathway by targeting PTEN

S Sheng, W Jiwen, Z Dexiang, Z Bohao… - Bioscience …, 2019 - academic.oup.com
Gallbladder carcinoma (GBC) is a highly lethal malignancy of the gastrointestinal tract.
Despite extensive research, the underlying molecular mechanism of GBC remains largely …

[HTML][HTML] EPDR1 is related to stages and metastasize in bladder cancer and can be used as a prognostic biomarker

Y Yang, H Zhang, Z Liu, F Zhao, G Liang - BMC urology, 2021 - Springer
Background Bladder cancer (BLCA) is a malignant urothelial carcinoma and has a high
mortality rate. EPDR1 (ependymin related 1) is a type II transmembrane protein and related …

[HTML][HTML] FOXO3a‑modulated DEPDC1 promotes malignant progression of nephroblastoma via the Wnt/β‑catenin signaling pathway

G Geng, Q Li, X Guo, Q Ni, Y Xu… - Molecular …, 2022 - spandidos-publications.com
Abstract DEP domain containing 1 (DEPDC1) and forkhead box transcription factor 3a
(FOXO3a) serve a role in tumor cells. To the best of our knowledge, however, the expression …