[HTML][HTML] An update on the morphology and molecular pathology of serrated colorectal polyps and associated carcinomas

RK Pai, M Bettington, A Srivastava, C Rosty - Modern Pathology, 2019 - Elsevier
Our understanding of serrated colorectal polyps has increased dramatically over the past
two decades and has led to a modern classification scheme for these lesions. Sessile …

[HTML][HTML] Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management

C Rosty, DG Hewett, IS Brown, BA Leggett… - Journal of …, 2013 - Springer
Approximately 30% of colorectal carcinomas develop via the serrated neoplasia pathway
characterized by widespread DNA methylation and frequent BRAF mutation. Serrated …

Serrated polyps and colorectal cancer: new pathway to malignancy

AE Noffsinger - Annual Review of Pathology: Mechanisms of …, 2009 - annualreviews.org
Until recently, two major forms of colorectal epithelial polyp were recognized: the adenoma
and the hyperplastic polyp. Adenomas were perceived to represent the precursor to …

Association of large serrated polyps with synchronous advanced colorectal neoplasia

D Li, C Jin, C McCulloch, S Kakar… - Official journal of the …, 2009 - journals.lww.com
OBJECTIVES: Serrated polyps of the colorectum are a histologically and genetically
heterogeneous group of lesions, which include classic hyperplasic polyps, sessile serrated …

Serrated colon polyps as precursors to colorectal cancer

S Sweetser, TC Smyrk, FA Sinicrope - Clinical Gastroenterology and …, 2013 - Elsevier
Identification of the serrated neoplasia pathway has improved our understanding of the
pathogenesis of colorectal cancer (CRC). Insights include an increased recognition of the …

Serrated polyps of the colon and rectum (hyperplastic polyps, sessile serrated adenomas, traditional serrated adenomas, and mixed polyps)—proposal for diagnostic …

DE Aust, GB Baretton… - Virchows Archiv, 2010 - Springer
Until recently, two major types of colorectal epithelial polyps were distinguished: the
adenoma and the hyperplastic polyp. While adenomas—because of their cytological atypia …

[HTML][HTML] Serrated polyps of the colorectum: is sessile serrated adenoma distinguishable from hyperplastic polyp in a daily practice?

D Sandmeier, W Seelentag, H Bouzourene - Virchows Archiv, 2007 - Springer
The distinction between serrated polyps of the colon is complex, particularly between
hyperplastic polyps (HP) and sessile serrated adenomas (SSA). Recent data show that SSA …

Serrated polyps of the large intestine: a morphologic and molecular review of an evolving concept

DC Snover, JR Jass… - American journal of …, 2005 - academic.oup.com
Serrated polyps of the large intestine, including traditional hyperplastic polyps, traditional
serrated adenomas, and more recently described sessile serrated adenomas, have gained …

[HTML][HTML] Sessile serrated adenoma: from identification to resection

B Bordaçahar, M Barret, B Terris, M Dhooge… - Digestive and Liver …, 2015 - Elsevier
Until the past two decades, almost all colorectal polyps were divided into two main groups:
hyperplastic polyps and adenomas. Sessile serrated adenomas presented endoscopic …

[HTML][HTML] Sessile serrated adenomas with dysplasia: morphological patterns and correlations with MLH1 immunohistochemistry

C Liu, NI Walker, BA Leggett, VLJ Whitehall… - Modern Pathology, 2017 - Elsevier
Sessile serrated adenomas are the precursor polyp of approximately 20% of colorectal
carcinomas. Sessile serrated adenomas with dysplasia are rarely encountered and …