Selective brain cooling reduces motor deficits induced by combined traumatic brain injury, hypoxemia and hemorrhagic shock

LY Leung, K Cardiff, X Yang… - Frontiers in …, 2018 - frontiersin.org
Selective brain cooling (SBC) can potentially maximize the neuroprotective benefits of
hypothermia for traumatic brain injury (TBI) patients without the complications of whole body …

Comprehensive evaluation of neuroprotection achieved by extended selective brain cooling therapy in a rat model of penetrating ballistic-like brain injury

XCM Lu, DA Shear, Y Deng-Bryant… - Therapeutic …, 2016 - liebertpub.com
Brain hypothermia has been considered as a promising alternative to whole-body
hypothermia in treating acute neurological disease, for example, traumatic brain injury …

Neuroprotection of selective brain cooling after penetrating ballistic-like brain injury in rats

G Wei, XCM Lu, DA Shear, X Yang… - Therapeutic …, 2011 - liebertpub.com
Induced hypothermia has been reported to provide neuroprotection against traumatic brain
injury. We recently developed a novel method of selective brain cooling (SBC) and …

Transient selective brain cooling confers neurovascular and functional protection from acute to chronic stages of ischemia/reperfusion brain injury

J Zhao, H Mu, L Liu, X Jiang, D Wu… - Journal of Cerebral …, 2019 - journals.sagepub.com
Ischemic injury can be alleviated by the judicious use of hypothermia. However, the optimal
regimens and the temporal kinetics of post-stroke neurovascular responses to hypothermic …

Extraluminal cooling of bilateral common carotid arteries as a method to achieve selective brain cooling for neuroprotection

G Wei, JA Hartings, X Yang, FC Tortella… - Journal of …, 2008 - liebertpub.com
Systemic cooling to achieve brain hypothermia has been investigated as a neuroprotective
therapy but can present serious adverse effects. Here we describe a novel method to …

Selective brain cooling after traumatic brain injury: effects of three different cooling methods—case report

T Westermaier, R Nickl, S Koehler… - … Surgery Part A …, 2017 - thieme-connect.com
Background In experimental models of neuronal damage, therapeutic hypothermia proved
to be a powerful neuroprotective method. In clinical studies of traumatic brain injury (TBI) …

Noninvasive selective brain cooling by head and neck cooling is protective in severe traumatic brain injury

W Qiu, H Shen, Y Zhang, W Wang, W Liu… - Journal of clinical …, 2006 - Elsevier
Therapeutic hypothermia is a promising treatment for patients with severe traumatic brain
injury (TBI). We present here the results of a study in which noninvasive selective brain …

A review of selective hypothermia in the management of traumatic brain injury

E Christian, G Zada, G Sung, SL Giannotta - Neurosurgical focus, 2008 - thejns.org
Object Traumatic brain injury (TBI) remains a significant cause of morbidity and death in the
US and worldwide. Resuscitative systemic hypothermia following TBI has been established …

Posttraumatic hypothermia followed by slow rewarming protects the cerebral microcirculation

E Suehiro, Y Ueda, EP Wei, HA Kontos… - Journal of …, 2003 - liebertpub.com
In the clinical and laboratory setting, multiple reports have suggested the efficacy of
hypothermia in blunting the damaging consequences of traumatic brain injury (TBI). With the …

Therapeutic hypothermia and targeted temperature management for traumatic brain injury: experimental and clinical experience

WD Dietrich, HM Bramlett - Brain circulation, 2017 - journals.lww.com
Traumatic brain injury (TBI) is a worldwide medical problem, and currently, there are few
therapeutic interventions that can protect the brain and improve functional outcomes in …