Assessment of inflow and washout of indocyanine green in the adult human brain by monitoring of diffuse reflectance at large source-detector separation

A Liebert, P Sawosz, D Milej… - … of biomedical optics, 2011 - spiedigitallibrary.org
Recently, it was shown in measurements carried out on humans that time-resolved near-
infrared reflectometry and fluorescence spectroscopy may allow for discrimination of …

Multiwavelength time-resolved near-infrared spectroscopy of the adult head: assessment of intracerebral and extracerebral absorption changes

A Gerega, D Milej, W Weigl, M Kacprzak… - Biomedical optics …, 2018 - opg.optica.org
An optical technique based on diffuse reflectance measurement combined with indocyanine
green (ICG) bolus tracking is extensively tested as a method for the clinical assessment of …

Multiwavelength time-resolved detection of fluorescence during the inflow of indocyanine green into the adult's brain

A Gerega, D Milej, W Weigl, M Botwicz… - … of biomedical optics, 2012 - spiedigitallibrary.org
Optical technique based on diffuse reflectance measurement combined with indocyanine
green (ICG) bolus tracking is extensively tested as a method for clinical assessment of brain …

Time-resolved detection of fluorescent light during inflow of ICG to the brain—a methodological study

D Milej, A Gerega, N Żołek, W Weigl… - Physics in Medicine …, 2012 - iopscience.iop.org
It was reported that time-resolved reflectance measurements carried out during inflow and
washout of an optical contrast agent may provide information on the blood supply to the …

Optical bedside monitoring of cerebral perfusion: technological and methodological advances applied in a study on acute ischemic stroke

O Steinkellner, C Gruber, H Wabnitz… - … of biomedical optics, 2010 - spiedigitallibrary.org
We present results of a clinical study on bedside perfusion monitoring of the human brain by
optical bolus tracking. We measure the kinetics of the contrast agent indocyanine green …

Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of …

A Liebert, H Wabnitz, J Steinbrink, H Obrig, M Möller… - Applied …, 2004 - opg.optica.org
We report on multidistance time-resolved diffuse reflectance spectroscopy of the head of a
healthy adult after intravenous administration of a bolus of indocyanine green. Intracerebral …

Bed-side assessment of cerebral perfusion in stroke patients based on optical monitoring of a dye bolus by time-resolved diffuse reflectance

A Liebert, H Wabnitz, J Steinbrink, M Möller… - Neuroimage, 2005 - Elsevier
We present a minimally invasive optical method, that is, multi-channel time-domain diffuse
near-infrared reflectometry of the head to assess cerebral blood perfusion that is applicable …

Separation of indocyanine green boluses in the human brain and scalp based on time-resolved in-vivo fluorescence measurements

A Jelzow, H Wabnitz, H Obrig… - Journal of …, 2012 - spiedigitallibrary.org
Non-invasive detection of fluorescence from the optical tracer indocyanine green is feasible
in the adult human brain when employing a time-domain technique with picosecond …

Broadband continuous-wave technique to measure baseline values and changes in the tissue chromophore concentrations

HZ Yeganeh, V Toronov, JT Elliott, M Diop… - Biomedical optics …, 2012 - opg.optica.org
We present a broad-band, continuous-wave spectral approach to quantify the baseline
optical properties of tissue and changes in the concentration of a chromophore, which can …

Optimization of the method for assessment of brain perfusion in humans using contrast-enhanced reflectometry: multidistance time-resolved measurements

D Milej, D Janusek, A Gerega… - Journal of …, 2015 - spiedigitallibrary.org
The aim of the study was to determine optimal measurement conditions for assessment of
brain perfusion with the use of optical contrast agent and time-resolved diffuse reflectometry …