In-silico screening of Acacia pennata and Bridelia retusa reveals pinocembrin-7-O-β-D-glucopyranoside as a promising β-lactamase inhibitor to combat antibiotic …
The β-lactamase of Pseudomonas aeruginosa is known to degrade β-lactam antibiotics
such as penicillins, cephalosporins, monobactams, and carbapenems. With the discovery of …
such as penicillins, cephalosporins, monobactams, and carbapenems. With the discovery of …
Insight into the screening of potential beta-lactamase inhibitors as anti-bacterial chemical agents through pharmacoinformatics study
P Parida, S Bhowmick, A Saha… - Journal of Biomolecular …, 2021 - Taylor & Francis
Drug resistance is an unsolved and major concern in the bacterial infection. Continuous
development of drug-resistance to the antibiotics exponentially rises the danger of bacterial …
development of drug-resistance to the antibiotics exponentially rises the danger of bacterial …
In vitro and computational studies of the β-lactamase inhibition and β-lactam potentiating properties of plant secondary metabolites
B Kongkham, A Yadav, MD Ojha… - Journal of …, 2023 - Taylor & Francis
Abstract β-lactam resistance in bacteria is primarily mediated through the production of β-
lactamases. Among the several strategies explored to mitigate the issue of β-lactam …
lactamases. Among the several strategies explored to mitigate the issue of β-lactam …
Biochemical and molecular docking-based strategies of Acalypha indica and Boerhavia diffusa extract by targeting bacterial strains and cancer proteins
Antibiotic-resistant microbes have emerged around the world, presenting a risk to health.
Plant-derived drugs have become a potential source for the production of antibiotic-resistant …
Plant-derived drugs have become a potential source for the production of antibiotic-resistant …
Identification of Phytochemicals with Inhibitory Potential Against Beta-lactamase Enzymes via Computer-aided Approach
GC Nwokebu, AB Adesina, CN Isibor, SA Aigbepue… - Bioorganic …, 2024 - Elsevier
Introduction Antibacterial drugs have been widely used for the past century to treat diseases,
but their efficacy has been limited by multi-resistant pathogens, particularly those that utilize …
but their efficacy has been limited by multi-resistant pathogens, particularly those that utilize …
Antibacterial and In Silico Evaluation of β-lactamase Inhibitory Potential of Pinus sylvestris L. (Scots Pine) Essential Oil
Antibiotic resistance remains one of the global challenges that needs urgent attention,
including finding alternative treatment options to conventional antibiotics and reversing …
including finding alternative treatment options to conventional antibiotics and reversing …
Investigating the antibacterial mechanism of Ampelopsis cantoniensis extracts against methicillin-resistant Staphylococcus aureus via in vitro and in silico analysis
Methicillin-resistant Staphylococcus aureus (MRSA) is a critical pathogen responsible for a
wide variety of serious infectious diseases in humans. The accelerated phenomena of drug …
wide variety of serious infectious diseases in humans. The accelerated phenomena of drug …
[HTML][HTML] In silico study of essential oil of Bambusa vulgaris leaves as an anti beta-lactamase compound
PW Anggini, SA Amanina, SR Asyura… - Molecular and Cellular …, 2022 - cellbiopharm.com
Background: Klebsiella pneumoniae is known as an extended spectrum beta (β)-lactamases
(ESBLs)-producing bacteria, which produces enzymes that cause resistance to β-lactam …
(ESBLs)-producing bacteria, which produces enzymes that cause resistance to β-lactam …
[HTML][HTML] Identification of natural inhibitor against L1 β-lactamase present in Stenotrophomonas maltophilia
Antibiotic resistance is threatening the medical industry in treating microbial infections. Many
organisms are acquiring antibiotic resistance because of the continuous use of the same …
organisms are acquiring antibiotic resistance because of the continuous use of the same …
Enhancing bactericidal strategy with selected aromatic compounds: in vitro and in silico study
Abstract β-Lactamases are enzymes that catalyze the hydrolysis of the β-lactam ring,
resulting in loss of function in β-lactam antibiotics. In this report, the inhibition of β-lactamase …
resulting in loss of function in β-lactam antibiotics. In this report, the inhibition of β-lactamase …