Diabetic nephropathy (DN) is a progressive microvascular diabetic complication. Growing
evidence shows that persistent mitochondrial dysfunction contributes to the progression of …

The role and nature of mitochondrial dysfunction in diabetic kidney disease (DKD) has been
extensively studied. Yet, the molecular drivers of mitochondrial remodeling in DKD are …

Mitochondrial medicine has experienced significant progress in recent years and is
expected to grow significantly in the near future, yielding many opportunities to translate …

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD) in
the United States and many other countries. DKD occurs through a variety of pathogenic …

The kidneys are highly metabolic organs that produce vast quantities of adenosine
triphosphate via oxidative phosphorylation and, as such, contain many mitochondria …

Background: Diabetic nephropathy (DN) is an important diabetic microvascular
complication, and it is becoming the leading cause of end-stage renal disease worldwide …

The role of mitochondria in diabetic complications has been viewed as a source of excess
superoxide production leading to cell dysfunction. However, with the lack of benefit of non …

Despite major improvements in the treatment of patients with diabetes mellitus, many
patients still suffer from progressive diabetic kidney disease. More research is needed to …

Globally, diabetes is the leading cause of chronic kidney disease and end-stage renal
disease, which are major risk factors for cardiovascular disease and death. Despite this …

Mitochondrial dysfunction is implicated in the pathogenesis of diabetic kidney disease
(DKD). Compared to the vast body of evidence from preclinical in vitro and in vivo studies …