A clinical overview of off-label use of gabapentinoid drugs

CW Goodman, AS Brett - JAMA internal medicine, 2019 - jamanetwork.com
Background The gabapentinoid drugs gabapentin and pregabalin were originally
developed as antiseizure drugs but now are prescribed mainly for treatment of pain. For …

[HTML][HTML] Gabapentin and pregabalin for pain—is increased prescribing a cause for concern?

CW Goodman, AS Brett - New England Journal of Medicine, 2017 - Mass Medical Soc
Gabapentin and Pregabalin for Pain — Is Increased Prescribing a Cause for Concern? |
New England Journal of Medicine Skip to main content The New England Journal of …

Trends in first gabapentin and pregabalin prescriptions in primary care in the United Kingdom, 1993-2017

F Montastruc, SY Loo, C Renoux - Jama, 2018 - jamanetwork.com
Methods| Using the Clinical Practice Research Datalink (CPRD), a UK database of primary
care medical records from more than 15 million patients, 5 we identified all patients …

Examination of the evidence for off-label use of gabapentin

A Mack - Journal of Managed Care Pharmacy, 2003 - jmcp.org
OBJECTIVES:(1) Describe the relevance of off-label use of gabapentin to managed care
pharmacy;(2) summarize recent FDA warnings and media reports related to off-label …

[HTML][HTML] Outcome reporting in industry-sponsored trials of gabapentin for off-label use

SS Vedula, L Bero, RW Scherer… - New England Journal of …, 2009 - Mass Medical Soc
Background There is good evidence of selective outcome reporting in published reports of
randomized trials. Methods We examined reporting practices for trials of gabapentin funded …

Gabapentin for chronic neuropathic pain

A Moore, S Derry, P Wiffen - Jama, 2018 - jamanetwork.com
Clinical Question Is gabapentin associated with pain relief in people with chronic
neuropathic pain? Bottom Line Oral gabapentin (1200-3600 mg/d for 4-12 weeks) for …

[引用][C] Gabapentin and pregabalin for the treatment of anxiety disorders

HK Greenblatt, DJ Greenblatt - Clinical pharmacology in drug …, 2018 - Wiley Online Library
Gabapentin and pregabalin are structurally related compounds which are classified as
gammaaminobutyric acid (GABA) analogues or gabapentinoids (Figure 1). Gabapentin …

Gabapentin for off-label use: evidence-based or cause for concern?

AM Peckham, KE Evoy, L Ochs… - … Abuse: Research and …, 2018 - journals.sagepub.com
Gabapentin is widely used in the United States for a number of off-label indications, often as
an alternative to opioid therapy. Increasing evidence has emerged suggesting that …

Gabapentin for acute and chronic pain

PJ Wiffen, HJ McQuay, J Edwards… - Cochrane database …, 1996 - cochranelibrary.com
Abstract Background February 2009: The authors are aware of unpublished trial data for
Gabapentin which could affect the results of this review. This information together with that …

[HTML][HTML] Gabapentinoid benefit and risk stratification: mechanisms over myth

H McAnally, U Bonnet, AD Kaye - Pain and therapy, 2020 - Springer
Introduction Recent years have seen a dramatic escalation of off-label prescribing for
gabapentin and pregabalin (gabapentinoids) owing in part to generic versions of each being …