[HTML][HTML] The impact of helminth-induced immunity on infection with bacteria or viruses

H Chen, Z Cao, M Liu, MS Diamond, X Jin - Veterinary Research, 2023 - Springer
Different human and animal pathogens trigger distinct immune responses in their hosts. The
infection of bacteria or viruses can trigger type I pro-inflammatory immune responses (eg …

Immunological interactions in helminths‐SARS CoV‐2 coinfection: Could old enemy be a friend today?

M Alrouji, HM Al‐Kuraishy, AI Al‐Gareeb… - Parasite …, 2023 - Wiley Online Library
Helminths are metazoan parasites affecting about one third of the worldwide population.
Chronic helminth infections (CHIs) confer immunological tolerance to harmless and self …

The Potential Nexus between Helminths and SARS‐CoV‐2 Infection: A Literature Review

HM Al-Kuraishy, AI Al-Gareeb, L Alkazmi… - Journal of …, 2023 - Wiley Online Library
Chronic helminth infections (CHIs) can induce immunological tolerance through the
upregulation of regulatory T cells. In coronavirus disease 2019 (COVID‐19), abnormal …

The influence of helminth immune regulation on COVID-19 clinical outcomes: is it beneficial or detrimental?

M Ademe, F Girma - Infection and Drug Resistance, 2021 - Taylor & Francis
Immunologically, chronic worm infections prevent themselves from strong immune
responses by skewing the host response towards a T helper 2 (Th2) type. The regulatory …

Helminths and COVID-19 susceptibility, disease progression, and vaccination efficacy

B Whitehead, S Christiansen, L Østergaard… - Trends in …, 2022 - cell.com
Almost 2 years into the coronavirus disease 2019 (COVID-19) pandemic, it remains to be
determined how helminths interact with severe acute respiratory syndrome coronavirus 2 …

Old friends meet a new foe: a potential role for immune-priming parasites in mitigating COVID-19 morbidity and mortality

TJ Cepon-Robins, TE Gildner - Evolution, Medicine, and Public …, 2020 - academic.oup.com
Abstract The novel virus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2),
and the associated Coronavirus Disease 2019 (COVID-19) represent a pathogen to which …

[HTML][HTML] COVID-19 and helminth infection: beyond the Th1/Th2 paradigm

AE Paniz-Mondolfi, JD Ramírez… - PLOS Neglected …, 2021 - journals.plos.org
In a recent commentary, Bradbury and colleagues raise concerns regarding the potential
influence of preexisting helminth infections on Coronavirus Disease 2019 (COVIDAU …

[HTML][HTML] SARS-CoV-2 and helminth co-infections, and environmental pollution exposure: An epidemiological and immunological perspective

P Naidoo, T Ghazi, AA Chuturgoon, RN Naidoo… - Environment …, 2021 - Elsevier
Soil-transmitted helminths infect billions of people globally, particularly those residing in low-
and middle-income regions with poor environmental sanitation and high levels of air and …

[HTML][HTML] Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2

P Desai, CE Karl, B Ying, CY Liang, T Garcia-Salum… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Although vaccines have reduced COVID-19 disease burden, their efficacy in helminth
infection endemic areas is not well characterized. We evaluated the impact of infection by …

Will helminth co-infection modulate COVID-19 severity in endemic regions?

RS Bradbury, D Piedrafita, A Greenhill… - Nature Reviews …, 2020 - nature.com
As COVID-19 spreads through the world, most cases to date are in middle-and high-income
nations. The impact on resource-poor nations remains unknown. Amongst many factors …