Here we review the emerging neurobiological understanding of the role of the brain's reward
system in the regulation of body weight in health and in disease. Common obesity is …

Obesity and other eating disorders are marked by dysregulations to brain metabolic,
hedonic, motivational, and sensory systems that control food intake. Classic approaches in …

'Hunger is the best spice'is an old and wise saying that acknowledges the fact that almost
any food tastes better when we are hungry. The neurobiological underpinnings of this lore …

The hormones insulin, leptin, and ghrelin have been demonstrated to act in the central
nervous system (CNS) as regulators of energy homeostasis, acting at medial hypothalamic …

The incidence of obesity is increasing at an alarming rate and this worldwide epidemic
represents a significant decrease in life span and quality of life of a large part of the affected …

The feelings of appetite and satiety involve complex interactions between hormones from
the gastrointestinal (GI) tract to the hypothalamus and subsequent feedback. Within the …

Almost all circulating gut peptides contribute to the control of food intake by signalling
satiety. One important exception is ghrelin, the only orexigenic peptide hormone thus far …

Food intake is tightly regulated by homeostatic and reward mechanisms and the adequate
function of both is necessary for the proper maintenance of energy balance. Ghrelin impacts …

Obesity is on the rise in all developed countries, and a large part of this epidemic has been
attributed to excess caloric intake, induced by ever present food cues and the easy …

Obesity has reached global epidemic proportions and creating an urgent need to
understand mechanisms underlying excessive and uncontrolled food intake. Ghrelin, the …