Quinazoline and quinazolinone as important medicinal scaffolds: a comparative patent review (2011–2016)

A Hameed, M Al-Rashida, M Uroos, SA Ali… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Quinazoline and quinazolinone scaffolds represent an important class of
biologically active nitrogen heterocyclic compounds. A variety of marketed drugs are based …

Synthesis and therapeutic potential of quinoline derivatives

S Narwal, S Kumar, PK Verma - Research on Chemical Intermediates, 2017 - Springer
Quinolines are nitrogen-containing bicyclic compounds that are widely found throughout
Nature in various forms. Quinoline derivatives are utilized in the areas of medicine, food …

Chemistry of the fumiquinazolines and structurally related alkaloids

DISP Resende, P Boonpothong, E Sousa… - Natural product …, 2019 - pubs.rsc.org
Covering: this review covers the literature from 1992 to 2018 To date, approximately 80
naturally-occurring secondary metabolites which are structurally-related to fumiquinazolines …

Biologically active quinoline and quinazoline alkaloids part I

XF Shang, SL Morris‐Natschke, YQ Liu… - Medicinal research …, 2018 - Wiley Online Library
Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic
compounds, have attracted tremendous attention from researchers worldwide since the 19th …

Aryne insertion reactions leading to bioactive fused quinazolinones: diastereoselective total synthesis of cruciferane

SD Vaidya, NP Argade - Organic letters, 2013 - ACS Publications
Insertion reactions of an in situ generated arynes to a variety of suitably substituted 1, 3-
quinazolin-4-ones have been demonstrated for a new efficient one-step approach to a …

[HTML][HTML] Recent advances in the synthesis of biologically and pharmaceutically active quinoline and its analogues: a review

A Weyesa, E Mulugeta - RSC advances, 2020 - pubs.rsc.org
Recently, quinoline has become an essential heterocyclic compound due to its versatile
applications in the fields of industrial and synthetic organic chemistry. It is a vital scaffold for …

Quinoline, quinazoline and acridone alkaloids

JP Michael - Natural product reports, 1997 - pubs.rsc.org
The overwhelming majority of quinoline alkaloids are found in the Rutaceae. In Table 1 are
listed new rutaceous quinoline alkaloids described in the period from July 1995 to June …

Natural quinazolinones: From a treasure house to promising anticancer leads

H Li, G Fu, W Zhong - European Journal of Medicinal Chemistry, 2023 - Elsevier
Despite great advances in the development of modern anticancer drugs, it is still challenging
to find safer and more effective ones due to a new spectrum of diseases and emerging drug …

Recent advances in the structural library of functionalized quinazoline and quinazolinone scaffolds: Synthetic approaches and multifarious applications

I Khan, A Ibrar, N Abbas, A Saeed - European Journal of Medicinal …, 2014 - Elsevier
Drug development has been a principal driving force in the rapid maturation of the field of
medicinal chemistry during the past several decades. During this period, the intriguing and …

One‐Pot, Three‐Component Synthesis of 2,3‐Dihydro‐4(1H)‐quinazolinones by Montmorillonite K‐10 as an Efficient and Reusable Catalyst

P Salehi, M Dabiri, M Baghbanzadeh… - Synthetic …, 2006 - Taylor & Francis
A wide range of mono‐and disubstituted dihydroquinazolinones were synthesised via
condensation of isatoic anhydride, primary amines, or ammonium salts with aromatic …