Mechanism of Sophorae Flavescentis Radix (Kushen) in treating NSCLC: Insights from miRNA-mRNA network analysis
Abstract Ethnopharmacological relevance Sophorae Flavescentis Radix (Kushen) is the
primary herb component of Compound Kushen Injection (CKI), an approved clinical …
primary herb component of Compound Kushen Injection (CKI), an approved clinical …
Sanguisorba officinalis L. suppresses non-small cell lung cancer via downregulating the PI3K/AKT/mTOR signaling pathway based on network pharmacology and …
H Li, J Lin, F Yang, J Deng, J Lai, J Zeng… - Frontiers in …, 2022 - frontiersin.org
Background: Non-small cell lung cancer (NSCLC) is the most common type of lung cancer.
Sanguisorba officinalis L.(SOL), a traditional Chinese herbal medicine called Diyu, has been …
Sanguisorba officinalis L.(SOL), a traditional Chinese herbal medicine called Diyu, has been …
Sophflarine A, a novel matrine-derived alkaloid from Sophora flavescens with therapeutic potential for non-small cell lung cancer through ROS-mediated pyroptosis …
D Luo, X Dai, H Tian, C Fan, H Xie, N Chen, J Wang… - Phytomedicine, 2023 - Elsevier
Background Novel compounds and more efficient treatment options are urgently needed for
the treatment of non-small cell lung cancer (NSCLC). The decoction of Sophora flavescens …
the treatment of non-small cell lung cancer (NSCLC). The decoction of Sophora flavescens …
Integrated Network Pharmacology and Experimental Verification to explore the molecular mechanism of Hedysarum Multijugum Maxim–Curcumae Rhizoma Herb Pair …
S Hu, M Ge, S Zhang, M Jiang, K Hu, L Gao - Frontiers in Oncology, 2022 - frontiersin.org
Background Hedysarum Multijugum Maxim–Curcumae Rhizoma (HMMCR), a well-known
herb pair in traditional Chinese medicine (TCM), has been widely used for the treatment of …
herb pair in traditional Chinese medicine (TCM), has been widely used for the treatment of …
Network pharmacology analysis, molecular docking integrated experimental verification reveal β-sitosterol as the active anti-NSCLC ingredient of Polygonatum …
W Cao, F Yuan, T Liu, R Yin - Journal of Ethnopharmacology, 2024 - Elsevier
Abstract Ethnopharmacological relevance Polygonatum cyrtonema Hua (Huangjing) is a
Chinese herb that is considered by ancient Chinese healers to have the effect of nourishing …
Chinese herb that is considered by ancient Chinese healers to have the effect of nourishing …
[HTML][HTML] Cytological effects of honokiol treatment and its potential mechanism of action in non-small cell lung cancer
J Zhang, Y Zhang, W Shen, R Fu, Z Ding, Y Zhen… - Biomedicine & …, 2019 - Elsevier
Purpose In this study, we aimed to explore key micro (mi) RNAs and their potential
regulatory mechanisms induced by honokiol treatment in non-small cell lung cancer …
regulatory mechanisms induced by honokiol treatment in non-small cell lung cancer …
Study on the material basis and action mechanisms of sophora davidii (Franch.) skeels flower extract in the treatment of non-small cell lung cancer
B Ye, P Chen, C Lin, C Zhang, L Li - Journal of Ethnopharmacology, 2023 - Elsevier
Abstract Ethnopharmacological relevance Sophora davidii (Franch.) Skeels Flower (SDF) is
a characteristic folk medicine in Yunnan and Guizhou, which can be used to prevent the …
a characteristic folk medicine in Yunnan and Guizhou, which can be used to prevent the …
Saucerneol attenuates nasopharyngeal carcinoma cells proliferation and metastasis through selectively targeting Grp94
Background Nasopharyngeal carcinoma (NPC) is highly prevalent in southern China. The
remote metastasis of advanced NPC requires chemotherapeutic treatments to reduce the …
remote metastasis of advanced NPC requires chemotherapeutic treatments to reduce the …
[HTML][HTML] The anti-cancerous mechanism of licochalcone A on human hepatoma cell HepG2 based on the miRNA omics
J Wang, X Zhang, Z Ni, E Elam, K Thakur, K Li… - Food Science and …, 2023 - Elsevier
To explore the function of licochalcone A as an anticancer phytochemical on HepG2 cells
and investigate its potential mechanisms, we analyzed the microRNAs (miRNAs) expression …
and investigate its potential mechanisms, we analyzed the microRNAs (miRNAs) expression …
[HTML][HTML] Chloroform extract from Sophora Tonkinensis Gagnep. inhibit proliferation, migration, invasion and promote apoptosis of nasopharyngeal carcinoma cells by …
Z Song, X Gong, C Ou, W Zhang, J Wang, C Yao… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Sophora Tonkinensis Gagnep.(STG) has been
used as a folk medicine for the treatment of different cancers, especially for nasopharyngeal …
used as a folk medicine for the treatment of different cancers, especially for nasopharyngeal …