IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response
MP Rubinstein, NA Lind, JF Purton… - Blood, The Journal …, 2008 - ashpublications.org
Although it is known that interleukin-7 (IL-7) and IL-15 influence the survival and turnover of
CD8+ T cells, less is known about how these cytokines affect different subsets during the …
CD8+ T cells, less is known about how these cytokines affect different subsets during the …
Interleukin 2-dependent and interleukin 2-independent pathways of regulation of thymocyte function by interleukin 6.
JM Le, G Fredrickson, LF Reis… - Proceedings of the …, 1988 - National Acad Sciences
Recombinant human interleukin 6 (IL-6), also termed B-cell-stimulatory factor 2 (BSF-2) or
interferon-beta 2, was found to stimulate the proliferation of mouse thymocytes costimulated …
interferon-beta 2, was found to stimulate the proliferation of mouse thymocytes costimulated …
IL-15 is required for sustained lymphopenia-driven proliferation and accumulation of CD8 T cells
MM Sandau, CJ Winstead… - The Journal of …, 2007 - journals.aai.org
Naive T cells undergo slow homeostatic proliferation in response to T cell lymphopenia,
which is also called lymphopenia-induced proliferation (LIP). IL-7 is critically required for this …
which is also called lymphopenia-induced proliferation (LIP). IL-7 is critically required for this …
Cellular sources and immune functions of interleukin-9
RJ Noelle, EC Nowak - Nature Reviews Immunology, 2010 - nature.com
Abstract Interleukin-9 (IL-9) has attracted renewed interest owing to the identification of its
expression by multiple T helper (TH) cell subsets, including TH2 cells, TH9 cells, TH17 cells …
expression by multiple T helper (TH) cell subsets, including TH2 cells, TH9 cells, TH17 cells …
Interleukin-7: Fuel for the autoimmune attack
H Dooms - Journal of autoimmunity, 2013 - Elsevier
Abstract Interleukin-7 (IL-7) is a critical survival factor for lymphocytes and recent studies
suggest targeting the IL-7/IL-7Rα pathway holds promise for the treatment of autoimmune …
suggest targeting the IL-7/IL-7Rα pathway holds promise for the treatment of autoimmune …
[HTML][HTML] Multiple choices: regulation of memory CD8 T cell generation and homeostasis by interleukin (IL)-7 and IL-15
M Prlic, L Lefrancois, SC Jameson - The Journal of experimental …, 2002 - ncbi.nlm.nih.gov
The generation of memory T cells in immune responses has been extensively studied over
recent years, yet the requirements for production and persistence of a functional memory …
recent years, yet the requirements for production and persistence of a functional memory …
Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cells
C Dong - Nature Reviews Immunology, 2006 - nature.com
Abstract CD4+ T helper 1 (TH1) and TH2 cells have long been regarded as two sides of a
coin in terms of adaptive immune responses. However, as I discuss here, this concept needs …
coin in terms of adaptive immune responses. However, as I discuss here, this concept needs …
CD25+CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production
T Barthlott, H Moncrieffe, M Veldhoen… - International …, 2005 - academic.oup.com
Maintenance of homeostasis in the immune system involves competition for resources
between T lymphocytes, which avoids the development of immune pathology seen in …
between T lymphocytes, which avoids the development of immune pathology seen in …
IL-17A-producing neutrophil-regulatory Tn lymphocytes
K Ley, E Smith, MA Stark - Immunologic research, 2006 - Springer
The proinflammatory cytokine IL-17A, mainly produced by specialized T cells, plays an
important homeostatic role in regulating neutrophil production and blood neutrophil counts …
important homeostatic role in regulating neutrophil production and blood neutrophil counts …
Interleukin-10 (Il-10) and viral-Il-10 strongly reduce antigen-specific human T-cell proliferation by diminishing the antigen-presenting capacity of monocytes via down …
RD Malefyt, J Haanen, H Spits, MG Roncarolo… - Journal of Experimental …, 1991 - iris.unisr.it
Abstract Interleukin 10 (IL-10) and viral IL-10 (v-IL-10) strongly reduced antigen-specific
proliferation of human T cells and CD4+ T cells clones when monocytes were used as …
proliferation of human T cells and CD4+ T cells clones when monocytes were used as …