Although it is known that interleukin-7 (IL-7) and IL-15 influence the survival and turnover of
CD8+ T cells, less is known about how these cytokines affect different subsets during the …

Recombinant human interleukin 6 (IL-6), also termed B-cell-stimulatory factor 2 (BSF-2) or
interferon-beta 2, was found to stimulate the proliferation of mouse thymocytes costimulated …

Naive T cells undergo slow homeostatic proliferation in response to T cell lymphopenia,
which is also called lymphopenia-induced proliferation (LIP). IL-7 is critically required for this …

Abstract Interleukin-9 (IL-9) has attracted renewed interest owing to the identification of its
expression by multiple T helper (TH) cell subsets, including TH2 cells, TH9 cells, TH17 cells …

Abstract Interleukin-7 (IL-7) is a critical survival factor for lymphocytes and recent studies
suggest targeting the IL-7/IL-7Rα pathway holds promise for the treatment of autoimmune …

The generation of memory T cells in immune responses has been extensively studied over
recent years, yet the requirements for production and persistence of a functional memory …

Abstract CD4+ T helper 1 (TH1) and TH2 cells have long been regarded as two sides of a
coin in terms of adaptive immune responses. However, as I discuss here, this concept needs …

Maintenance of homeostasis in the immune system involves competition for resources
between T lymphocytes, which avoids the development of immune pathology seen in …

The proinflammatory cytokine IL-17A, mainly produced by specialized T cells, plays an
important homeostatic role in regulating neutrophil production and blood neutrophil counts …

Abstract Interleukin 10 (IL-10) and viral IL-10 (v-IL-10) strongly reduced antigen-specific
proliferation of human T cells and CD4+ T cells clones when monocytes were used as …