[PDF][PDF] Role of epigenetic modifications in the aberrant CYP19A1 gene expression in polycystic ovary syndrome

E Hosseini, M Shahhoseini, P Afsharian… - Archives of Medical …, 2019 - termedia.pl
Results The data demonstrate a significant increase in global occupancy levels of MeCP2
and H3K9ac markers and a decrease of H3K9me2 to chromatin in CCs of PCOS patients vs …

Promoter methylation of CYP19A1 gene in Chinese polycystic ovary syndrome patients

YY Yu, CX Sun, YK Liu, Y Li, L Wang… - Gynecologic and …, 2013 - karger.com
Aims: This study aimed to examine the methylation status of the CYP19A1 promoter region
in Chinese polycystic ovary syndrome (PCOS) patients. Methods: A case-control study was …

CYP19A1 gene expression in patients with polycystic ovarian syndrome

R Panghiyangani, P Soeharso… - Journal of Human …, 2020 - journals.lww.com
Aims: This research analyzed the role of the aromatase gene (CYP19A1) in PCOS
pathogenesis. Settings and Design: This study used an observational, cross-sectional …

CYP1A1 gene polymorphism and polycystic ovary syndrome

I Esinler, D Aktas, U Otegen, M Alikasifoglu… - Reproductive …, 2008 - Elsevier
The aim of this study was to assess the rates of variant alleles of cytochrome P4501A1
(CYP1A1) in patients with polycystic ovary syndrome (PCOS). It was designed as a case …

Epigenetic alterations of CYP19A1 gene in Cumulus cells and its relevance to infertility in endometriosis

E Hosseini, F Mehraein, M Shahhoseini… - Journal of assisted …, 2016 - Springer
Purpose The purpose of the present study was to investigate the epigenetic mechanisms
responsible for the aberrant aromatase expression (CYP19A1) in Cumulus Cells (CCs) of …

Relation between aromatase gene CYP19 variation and hyperandrogenism in polycystic ovary syndrome Egyptian women

RA Mostafa, MM Al-Sherbeeny, IA Abdelazim… - Journal of Infertility and …, 2016 - dormaj.org
Background: This study designed to detect the relation between the aromatase CYP19 gene
SNP50 variation and hyperandrogenism in polycystic ovary syndrome (PCOS) Egyptian …

Polymorphism in CYP11alpha and CYP17 genes and the etiology of hyperandrogenism in patients with polycystic ovary syndrome

MS Perez, GE Cerrone, H Benencia, N Marquez… - Medicina, 2008 - europepmc.org
The polycystic ovary syndrome (PCOS) is a heterogeneous multifactorial endocrine
metabolic disorder with genetic predisposition affecting 6% of women in the reproductive …

Investigations on the genetic polymorphism in the region of CYP17 gene encoding 5′-UTR in patients with polycystic ovarian syndrome

B Marszalek, M Laciński, N Babych… - Gynecological …, 2001 - Taylor & Francis
Polycystic ovarian syndrome (PCOS) is a prevalent endocrine disorder, which is the most
common cause of anovulatory infertility and hirsutism. It is caused by an overproduction of …

[HTML][HTML] The CYP17 MSP AI (T-34C) and CYP19A1 (Trp39Arg) variants in polycystic ovary syndrome: A case-control study

Z Rahimi, E Mohammadi - International Journal of Reproductive …, 2019 - ncbi.nlm.nih.gov
Background Polycystic ovary syndrome (PCOS) is a common and chronic disorder of
endocrine glands where genetic factors play a major role in the susceptibility to the disease …

[HTML][HTML] CYP19 gene: a genetic modifier of polycystic ovary syndrome phenotype

N Xita, L Lazaros, I Georgiou, A Tsatsoulis - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To evaluate the possible contribution of the (TTTA) n polymorphism of
aromatase gene (CYP19) to the hyperandrogenic phenotype of polycystic ovary syndrome …