Background Burkholderia pseudomallei is a soil-dwelling saprophyte and the cause of
melioidosis. Horizontal gene transfer contributes to the genetic diversity of this pathogen and …

Background Burkholderia pseudomallei is the etiologic agent of melioidosis, a significant
cause of morbidity and mortality where this infection is endemic. Genomic differences …

Background Burkholderia thailandensis is a non-pathogenic environmental saprophyte
closely related to Burkholderia pseudomallei, the causative agent of the often fatal animal …

Background The facultative, intracellular bacterium Burkholderia pseudomallei is the
causative agent of melioidosis, a serious infectious disease of humans and animals. We …

Natural isolates of Burkholderia pseudomallei (Bp), the causative agent of melioidosis, can
exhibit significant ecological flexibility that is likely reflective of a dynamic genome. Using …

The human diseases melioidosis and glanders are caused by the bacteria Burkholderia
pseudomallei and B. mallei respectively, and both species are regarded as potential …

Burkholderia pseudomallei is a Gram-negative environmental bacterium that causes
melioidosis, a disease of high mortality in humans and animals. Multilocus sequence typing …

We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia
pseudomallei isolated from seven body sites of a patient with acute disseminated …

The pangenomic diversity in Burkholderia pseudomallei is high, with approximately 5.8% of
the genome consisting of genomic islands. Genomic islands are known hotspots for …

Little is currently known about bacterial pathogen evolution and adaptation within the host
during acute infection. Previous studies of Burkholderia pseudomallei, the etiologic agent of …