Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei

MTG Holden, RW Titball, SJ Peacock… - Proceedings of the …, 2004 - National Acad Sciences
Burkholderia pseudomallei is a recognized biothreat agent and the causative agent of
melioidosis. This Gram-negative bacterium exists as a soil saprophyte in melioidosis …

Nonrandom Distribution of Burkholderia pseudomallei Clones in Relation to Geographical Location and Virulence

M Vesaratchavest, S Tumapa, NPJ Day… - Journal of clinical …, 2006 - Am Soc Microbiol
Burkholderia pseudomallei is a soil-dwelling saprophyte and the causative agent of
melioidosis, a life-threatening human infection. Most cases are reported from northeast …

[HTML][HTML] Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia …

Y Yu, HS Kim, HH Chua, CH Lin, SH Sim, D Lin… - BMC microbiology, 2006 - Springer
Abstract Background The Gram-negative bacterium Burkholderia pseudomallei (Bp) is the
causative agent of the human disease melioidosis. To understand the evolutionary …

[HTML][HTML] Genetic variation associated with infection and the environment in the accidental pathogen Burkholderia pseudomallei

C Chewapreecha, AE Mather, SR Harris… - Communications …, 2019 - nature.com
The environmental bacterium Burkholderia pseudomallei causes melioidosis, an important
endemic human disease in tropical and sub-tropical countries. This bacterium occupies …

A Horizontal Gene Transfer Event Defines Two Distinct Groups within Burkholderia pseudomallei That Have Dissimilar Geographic Distributions

A Tuanyok, RK Auerbach, TS Brettin… - Journal of …, 2007 - Am Soc Microbiol
Burkholderia pseudomallei is the etiologic agent of melioidosis. Many disease
manifestations are associated with melioidosis, and the mechanisms causing this variation …

Integrative Genomic, Transcriptional, and Proteomic Diversity in Natural Isolates of the Human Pathogen Burkholderia pseudomallei

K Ou, C Ong, SY Koh, F Rodrigues, SH Sim… - Journal of …, 2005 - Am Soc Microbiol
Natural isolates of pathogenic bacteria can exhibit a broad range of phenotypic traits. To
investigate the molecular mechanisms contributing to such phenotypic variability, we …

[HTML][HTML] Genomic Islands as a Marker to Differentiate between Clinical and Environmental Burkholderia pseudomallei

T Bartpho, T Wongsurawat, S Wongratanacheewin… - PloS one, 2012 - journals.plos.org
Burkholderia pseudomallei, as a saprophytic bacterium that can cause a severe sepsis
disease named melioidosis, has preserved several extra genes in its genome for survival …

Use of a Variable Amplicon Typing Scheme Reveals Considerable Variation in the Accessory Genomes of Isolates of Burkholderia pseudomallei

K Duangsonk, D Gal, M Mayo, CA Hart… - Journal of clinical …, 2006 - Am Soc Microbiol
Melioidosis, a disease caused by the bacterium Burkholderia pseudomallei, is endemic in
southeast Asia and northern Australia. We used suppression subtractive hybridization (SSH) …

Genomic Diversity of Burkholderia pseudomallei Clinical Isolates: Subtractive Hybridization Reveals a Burkholderia mallei-Specific Prophage in B. pseudomallei …

D DeShazer - Journal of bacteriology, 2004 - Am Soc Microbiol
Burkholderia pseudomallei is the etiologic agent of the disease melioidosis and is a
category B biological threat agent. The genomic sequence of B. pseudomallei K96243 was …

Development and validation of a Burkholderia pseudomallei core genome multilocus sequence typing scheme to facilitate molecular surveillance

S Lichtenegger, TT Trinh, K Assig, K Prior… - Journal of Clinical …, 2021 - Am Soc Microbiol
Burkholderia pseudomallei causes the severe disease melioidosis. Whole-genome
sequencing (WGS)-based typing methods currently offer the highest resolution for molecular …